9th International Conference on Bipolar Disorder, June 9-11, 2011, David L. Lawrence Convention Center, Pittsburgh, PA


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CONFERENCE SCHEDULE 

DAY 1: THURSDAY, JUNE 9, 2011 &

  7:45 a.m. Registration
 
  8:30 a.m.



8:35 a.m.

Introduction

David J. Kupfer, MD

Bio | Slides & Video

Opening Remarks
David A. Lewis, MD

Bio | Slides & Video
 

  8:45 a.m. 
SYMPOSIUM I – Medical Life Style Management: Theory and Interventions (e.g. Diabetes, Hypertension, Obesity)
Chair -- Fouzia Laghrissi-Thode, MD Bio

Health benefits to seeking synchrony, harmony and regulation: sleep and circadian rhythms in bipolar disorder
Allison Harvey, PhD
Bio Slides & Video

Bipolar disorder and cardiometabolic diseases: a risky combination
Fouzia Laghrissi-Thode, MD
Bio Slides & Video

Prevalence and treatment of cardiometabolic conditions in patients with bipolar disorder
Benjamin I. Goldstein, MD
Bio | Slides & Video

Changing health related behaviors: Can real-time interventions improve the course of bipolar disorder
Michael J. Ostacher, MD, PhD
Bio | Slides & Video
  10:15 a.m. Break
 
  10:30 a.m.

SYMPOSIUM II – Bipolar Disorder and the DSM
Chair -- Carlos A. Zarate, MD
Bio |Slides & Video

Evidence-based efforts to re-define bipolar disorders
Jules Angst, MD
Bio |Slides & Video

Proposed revisions to the concept of mixed episodes in DSM-5: the path traveled
Ellen Frank, PhD
Bio |Slides & Video

The debate on duration criteria of hypomanic episodes:  agreements, disagreements, and proposed solutions in DSM-5

Trisha Suppes, MD, PhD
Bio |Slides & Video

  12:00 p.m. Lunch (on your own)
 
 

1:00 p.m.

Report from the National Institute on Drug Abuse

Nora D. Volkow, MD
Bio |Slides & Video
 

  2:30 p.m. Break
 
  2:45 p.m. Concurrent Sessions I
 
   

T1.  Current Status of Child and Adolescent Bipolar Disorder

David A. Axelson, MD (Bio) and Boris Birmaher, MD (Bio)
Slides & Video
 

   

T2.  Debates in Bipolar Disorder: Are Atypical Antipsychotics Overused in Bipolar Disorder                       
Moderator --
Marion Leboyer, MD, PhD

Charles L. Bowden, MD, (Bio), Trisha Suppes, MD, PhD, (Bio) and Michael E. Thase, MD (Bio)
Slides & Audio
 

    T3. Ask the Expert: Clinical Case Conference                       
Mark Frye, MD (Bio) and Terence Ketter, MD (Bio)

Slides & Audio
 
    T4. Clinical Trial Design
John Geddes, MD, FRC Psych (Bio) and Amir Kalali, MD (Bio)
Slides &
Audio
 
    T5. Rhythms, Neuroimaging, and Bipolar Disorder
Ellen Frank, PhD (Bio) and Mary Phillips, MD (Bio)
Slides &
Audio
 
    T6. Glutamate Research in Bipolar Disorder
Chair -- Joseph Calabrese, MD
Nancy DiazGranados, MD, MS (Bio), Dost Ongur, MD, PhD (Bio) and Bryan K. Tolliver, MD, PhD (Bio)
Slides & Audio
 
    T7. Pregnancy and Bipolar Disorder
Adele Viguera, MD (Bio) and Katherine L. Wisner, MD (Bio)
Slides & Audio
 
  4:15 p.m. Adjournment  
 
  4:30 p.m.--
6:00 p.m.
Poster Session I
 
  7:00 p.m. Reception and Lilly Fellows Award Ceremony
Grand Concourse Restaurant
  
     
  DAY 2: FRIDAY, JUNE 10, 2011
 
  7:45 a.m.  Registration
 
  8:30 a.m.

Introduction
Ellen Frank, PhD
Bio | Slides & Video
 

  8:45 a.m. SYMPOSIUM III – Strategies for “Moving” Biology Forward
Chair -- Marion Leboyer, MD (Bio)

Synergizing transcriptome and genome-wide association studies in neuropsychiatric disorders
Etienne Sibille, PhD
Bio | Slides & Video

Inflammatory markers: moving biology forward in the diagnosis and treatment of mania
Faith B. Dickerson, PhD, MPH (Bio) and Robert H. Yolken, MD (Bio)
Slides & Video

Mitochondrial dysfunction and oxidative stress in bipolar disorder
L. Trevor Young, MD, PhD, FRCPC
Bio | Slides & Video
 
  10:15 a.m. Break
 
  10:30 a.m.  SYMPOSIUM IV – Cognition (Basic and Functional)                            
Chair -- Guy Goodwin, DPhil, FMedSci (Bio)

Cognitive impairments: a re-analysis of a large data set
Corin Bourne, DPhil
Bio | Slides & Video

Cognitive biases: contributions to risk of relapse and recovery
Guy Goodwin, DPhil, FMedSci
Bio | Slides & Video

The neurobiology of cognitive abnormalities in bipolar disorder
Stephen M. Strakowski, MD
Bio | Slides & Video
 
  12:00 p.m. Lunch (on your own)
 
  1:00 p.m. Concurrent Sessions II
 
    F1.  Debates in Bipolar Disorder: Antidepressants Are Ineffective for Bipolar Depression

Moderator -- Lakshmi N. Yatham, MB, FRCPC  (Bio)

John Geddes, MD, FRC Psych (Bio) and S. Nassir Ghaemi, MD, MPH (Bio)
Slides & Video

 

    F2. Clinical Case Conferences: Perspectives on Treatment from around the World
Chair -- Samuel Gershon, MD (Bio)
Guy Goodwin, DPhil, FMedSci (Bio), Paul Grof, MD, PhD, FRCPC (Bio) and Gin Malhi, MBChB, MRCPsych, FRANZCP, MD (Bio)
Slides & Audio
 
    F4. Cognitive Behavioral Therapy
Noreen Reilly-Harrington, PhD (Bio)
Slides & Audio
 
   

F5.  Family-Focused Treatment

Elizabeth L. George, PhD (Bio), Benjamin I. Goldstein, MD (Bio) and David J. Miklowitz, PhD (Bio)
Slides & Audio
 

    F6. Interpersonal and Social Rhythms Therapy
Debra Frankel, DCSW  (Bio) and Jodi M. Gonzalez, PhD (Bio) and Holly A. Swartz, MD (Bio)
Slides & Audio
 
    F7. Psychoeducation and Bipolar Disorder
Francesc Colom, PsyD, MSc, PhD (Bio) and Eduard Vieta, MD, PhD (Bio)
Slides & Audio
 
   

F8.  Life Goals Collaborative Care

Mark S. Bauer, MD (Bio) and Amy M. Kilbourne, PhD, MPH (Bio)
Slides & Audio
 

  2:30 p.m. Break
 
  2:45 p.m. 

Concurrent Rapid Communication Session (I and II)
 

Session I:
Chair -- Michael E. Thase, MD

Comparison between clinical characteristics of suicide attempters and non-attempters in a sample of bipolar disorder patients with
mania as first episode polarity

Lena N. Abreu, MD
Slides & Video

Cumulative morbidity and prognostic staging of illness in the Systematic Treatment Enhancement Program for
Bipolar Disorder (STEP-BD)

Michael Berk, MD, PhD
Slides & Video

CEQUEL: A Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy,
(and folic acid versus placebo) in people with bipolar depression: a 2x2 factorial randomised trial

Alexandra Gardiner, BSc (Hons)
Slides & Video

Cognitive deficits are an important determinant of functional deficits in bipolar disorder: Baseline results from LiTMUS
Dan V. Iosifescu, MD, MSc
Slides & Video

Predominance of manic episodes in the course of bipolar disorder in India
Jagadisha Thirthalli, MD
Slides & Video

Mental disorders in offspring of parents with bipolar and major depressive disorders
Martin Preisig, MD
Slides & Video

Disturbances in the hypothalamic-pituitary-adrenal (HPA) axis in bipolar patients: can they explain the relationship between
depression and cognitive functioning?

Rixt Riemersma-van der Lek, MD, PhD
Slides & Video

Session II
Chair -- Etienne Sibille, PhD

Progressive neurostructural changes in patients with bipolar disorder
Caleb M. Adler, MD
Slides & Audio

Increased levels of protein oxidation in synaptosomal but not mitochondrial proteins from postmortem prefrontal cortex of 
subjects with bipolar disorder
Ana C. Andreazza, PharmD
Slides & Audio

Elevated body mass index is associated with reduced hippocampal N-acetylaspartate in first-episode mania patients 
but not in healthy subjects
David J. Bond, MD, FRCPC
Slides & Audio

Increased striatal response to positive stimuli in bipolar patients compare to controls. To what extent do bipolar I and 
bipolar II patients share this phenotype? 
Xavier Caseras, PhD, MSc
Slides & Audio

The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
Torbjørn Elvsåshagen, MD
Slides & Audio

The incidence of sleep apnea in bipolar disorders
Tamms F. Kelly, MD
Slides & Audio

Emotion regulation and functional magnetic resonance imaging in bipolar II depression vs. major depressive disorder 
Nathalie Vizueta, PhD
Slides & Audio
  4:15 p.m. Adjournment
 
 
  4:30 p.m.  --6:00 p.m. Poster Session II
 
  7:30 p.m.

Dinner and Mogens Schou Awards

Carnegie Museums of Pittsburgh

Video

     
  DAY 3: SATURDAY, JUNE 11, 2011
     
  7:45 a.m.  Registration
 
  8:30 a.m.

Introduction

Michael E. Thase, MD (Bio)
 

  8:45 a.m.      Concurrent Sessions III
    S1. Controversies in Bipolar Disorder:  Is Pediatric Bipolar Disorder Overdiagnosed in the US?
Boris Birmaher, MD (Bio) and Gabrielle A. Carlson, MD (Bio)
Slides & Video
 
    S2. Recovery
Toni R. Ballard, MA (Bio) and Maria Silva (Bio)
Slides & Audio
 
    S3. European and United States Consortia
Andrew A. Nierenberg, MD
(Bio), Michael E. Thase, MD (Bio) and Eduard Vieta, MD, PhD (Bio)
Slides & Audio
 
  S4. Geriatrics and Bipolar Disorder
Chair -- Martha Sajatovic, MD (Bio)
Brent Forester, MD (Bio) and Ariel G. Gildengers, MD (Bio)
Slides & Audio
 
 
8:45 a.m.

Advanced Workshops

S6A.  Interpersonal and Social Rhythms Therapy

Ellen Frank, PhD (Bio) and Holly A. Swartz, MD (Bio)

Slides & Audio
 

S7A.  Family-Focused Therapy in Adolescents 

David A. Axelson, MD (Bio) and David J. Miklowitz, PhD (Bio)
Slides & Audio
 

  10:15 a.m.  Break
 
  10:30 a.m.

SYMPOSIUM V – New Approaches to Somatic Treatment

Chair -- Mauricio Tohen, MD, DrPH, MBA
Bio | Slides & Video

Comparative effectiveness methodology in trials for bipolar disorder
Andrew C. Leon, PhD
Bio | Slides & Video

New insight into the neurobiology of bipolar disorder and the development of rapid-acting antidepressants and biomarkers of response
Carlos A. Zarate, MD
Bio | Slides & Video
 

  12:00 p.m.  Lunch (on your own)
 
  1:00 p.m. SYMPOSIUM VI – International Society for Bipolar Disorder (ISBD) Task Force Reports
Chair -- Michael Berk, MD, PhD

Mauricio Tohen, MD, DrPH, MBA (Clinical Trial Design) Bio |Slides and Video
L. Trevor Young, MD, PhD, FRCPC (Biomarkers) Bio |Slides and Video
Stephen M. Strakowski, MD (Neuroimaging) Bio |Slides and Video
Sophia Frangou, MD, PhD (Cognition) Bio |Slides and Video
 
   3:00 p.m. Meet the Doctors

Treatment of Child and Adolescent Bipolar Disorder
David A. Axelson, MD (Bio)
 
Physical Health Issues in Bipolar Disorder
Benjamin I. Goldstein, MD (Bio)

Treatment of Adult Bipolar Disorder
Roger F. Haskett, MD (Bio)

Bipolar II and Bipolar Spectrum Disorders
David J. Miklowitz, PhD (Bio)
 
  4:15 p.m. Adjournment