SIXTH INTERNATIONAL CONFERENCE 
ON BIPOLAR DISORDER

June 16-18, 2005


David L. Lawrence Convention Center
Pittsburgh, Pennsylvania


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DAY 1: THURSDAY, JUNE 16, 2005
7:45 a.m. Registration
Continental Breakfast
 
8:30 a.m. Introduction
David J. Kupfer, M.D.
 
  Setting the Stage
Lydia Lewis
 
8:45 a.m.

Symposium I
Rational Polypharmacy: Can We Treat Bipolar Disorder with Fewer Than Five Medications?
--Chair: Samuel Gershon, MD                                      

"Polypharmacy for Treatment of Acute Mania:  Is It Rational Prescribing or Pill Pushing?"
--Lakshmi N. Yatham, M.B., FRCPC

"Evaluating Treatment Sequences for Bipolar Depression"
--Michael E. Thase, M.D.

"Simplifying the Complex:  Maintenance Treatment of Bipolar Disorder"
--Paul E. Keck, Jr., M.D
                                                                                                 
Top

10:15 a.m. Break
 
10:40 a.m.

Symposium II 
What Can Neurobiology, Imaging and Genetics Tell Us about Treatment of Bipolar Disorder?
--Chair: Edward M. Scolnick, M.D

"Similarities and Differences in the Epidemiology, Genetics, and Imaging of Bipolar Disorder and Schizophrenia"
--Robin M. Murray, M.D.

"What Can Genetics Tell Us about Treatment of Bipolar Disorder"
--J. Raymond DePaulo Jr., M.D.

"Combined Genomic and Proteomic Studies Identify Novel Targets in the Treatment of Severe Mood Disorders"

--Husseini K. Manji, M.D.

"Autoimmune Thyroiditis, a Possible Endophenotype of Bipolar Disorder?"
--Willem Nolen, M.D., Ph.D.

12:00 p.m. Lunch (on your own)
 
1:00 p.m.  Report from the National Institute of Mental Health
“NIMH Update”
- Thomas R. Insel, M.D.
 
2:30 p.m. Break
2:45 p.m. Concurrent Sessions I

T1.  Stanley Bipolar Network Update
Lori Altshuler, M.D

Mark Frye, M.D.
Ralph W. Kupka, M.D..
Robert M. Post, M.D.

T2.  The Use of Antidepressants in the Treatment of Bipolar Disorder

John R. Geddes, M.D., FRCPsych
Philip Mitchell, M.D., FRANZC, FRCPsych

T3.  Minimizing Polypharmacy: Strategies and Tactics

Charles L. Bowden, M.D.

T4.  Treatment Algorithms for Bipolar  Disorder

Sagar V. Parikh, M.D., FRCPC
Trisha  Suppes, M.D, Ph.D.

T5.  Placebos in Clinical Trials:  Design and Ethical Considerations

Helena Kraemer, Ph.D.
Fouzia Laghrissi-Thode, M.D.
Laura Roberts, M.D.

T6.  What Are the Limits of Psychosocial Treatment for Bipolar Disorder?
Francesc Colom, Psy.D., M.Sc., Ph.D.
David J. Miklowitz, Ph.D.
Jan Scott, M.D., FRCPsych

T7.  Managing Substance Abuse in Patients with Bipolar Disorder
Omar Elhaj, M.D.
Valentim Gentil, M.D., Ph.D.
Ihsan Salloum, M.D.

4:15 p.m. Adjournment
 
4:30 p.m. -
6:00 p.m.
Poster Session
7:00 p.m. -
10:00 p.m.
Reception                                                                                 Top
 

DAY 2: FRIDAY, JUNE 17, 2006 

7:45 a.m. Registration
Continental Breakfast
 
8:30 a.m.

Introduction
Ellen Frank, Ph.D.                                    

Setting the Stage
Kate Pravera, Ph.D.
 

8:45 a.m.

Symposium III
The Bipolar Spectrum:  Epidemiologic  and Clinical  Perspectives

 --Chair: Athanasios Koukopoulos, M.D.

"The Bipolar Spectrum:  Epidemiology and Clinical Perspectives"
--Jules Angst, M.D./Kathleen Merikangas, Ph.D.

"Threshold and Subthreshold Mania in Mood and Anxiety Disorders"
--Giovanni B. Cassano, M.D.

"Prevalence and Effects of Mood Disorders on Role Performance in the United States"
--Ronald C. Kessler, Ph.D.

10:15 a.m. Break
10:30 a.m.

Symposium IV
The Burden of Bipolar Disorder: Medical Illness, Suicide and Cognitive Impairment

--Chair:  Gregory E. Simon, M.D., M.P.H.

"What Kind of Psychosocial Intervention Should Be Used with Medically Burdened Patients?  Findings from the Pittsburgh Study of Maintenance Therapies in Bipolar Disorder."
--Ellen Frank, Ph.D.

"Cognitive Neuroscience and Bipolar Disorder:  New Insights into Relevant Outcomes and Mechanisms of Disease"
--Guy Goodwin, M.D.

"Reducing Suicidality in Bipolar Disorder:  Refinement of Risk Factors and Dilemmas in Treatment Development Research for Suicide Prevention"
--Lauren B. Marangell, M.D.
 

12:00 p.m. Lunch (on your own)
1:00 p.m. Concurrent Sessions II

F1. Neuroimaging in Bipolar Disorder
Wayne Drevets, M.D.
Mary Phillips, M.D.


F2. Diagnostic Issues and Nosology - Adults

Bruno Müller-Oerlinghausen, Dr.med.
Gary S. Sachs, M.D.

F3. Diagnostic Issues and Nosology Children and Adolescents

David A. Axelson, M.D.
Robert L. Findling, M.D.

F4. The Role of Complementary and Alternative Medicine (CAM) in Bipolar Disorder
Benoit H. Mulsant, M.D.
Trisha Suppes, M.D., Ph.D.

F5. Post-Traumatic Stress Disorder Michael
Otto, Ph.D.
Naomi M. Simon, M.D.

F6. Managing Eating Disorders and Obesity in Patients with Bipolar Disorder
Susan L. McElroy, M.D.

F7. Medical Monitoring: Who Should Be Responsible for Which Conditions: What Should Be Monitored and When?

Andrea Fagiolini, M.D.
David E. Kelley, M.D.
Steven E. Reis, M.D.

F8. The Functional and Economic Burden of Bipolar Disorder
Mark S. Bauer, M.D.
Anne Berghoefer, Dr.med.
Amy M. Kilbourne, Ph.D., M.P.H.                                                 
Top

2:30 p.m. Break
2:45 p.m. Concurrent Rapid Communication Sessions Session I

Chair: Carlos A. Zarate Jr., M.D.
“Language Processing in Euthymic Bipolar I Disorder Evidence for Altered Neural Network Engagement”

--Vivienne A. Curtis, MBBS

“Genome-Wide Scan of Early Onset Bipolar Affective Disorder in 70 European Families”
--Marion Leboyer, M.D., Ph.D.

“Cortical Abnormalities in Treated and Untreated Bipolar Disorder as Investigated with Voxel Based Morphometry”
--Allison C. Nugent, Ph.D.

“The Neural Basis of Impulse Dyscontrol in Mania: An fMRI Study of a Stop-Signal Task”
--Stephen M. Strakowski, M.D.

“Cerebral Metabolic Changes in Bipolar Depressed Patients Treated with the D2/D3 Receptor Agonist Pramipexole”
--Carlos A. Zarate Jr., M.D.

“Lithium as a Protective Factor for Cognitive Decline in Elderly Patients with Bipolar Disorder”
--Stevin P. Zung, M.D.

Session II:
Chair: Allan H. Young, M.D., Ph.D.

“Lithium Prevents Suicidal Acts in Manic-Depressive Patients”

--Ross J. Baldessarini, M.D.

“The Utility, Development and Validation of the Bipolar Depression Rating Scale (BDRS)”
--Michael Berk, M.D., Ph.D.

“Differential Roles of Adjunctive Antidepressants in Bipolar II Compared to Bipolar I Disorder”
--Terence A. Ketter, M.D.

“Cognitive Behavior Therapy and Supportive Therapy for Bipolar Disorders - Results of the 3-Month-Follow-Up of a Randomized Controlled Trial”
--Thomas D. Meyer, Ph.D.


“The Bipolar Spectrum: Evidence from Family Study Data”
--Martin Preisig, M.D., M.P.H.

“Meta-Analysis of the Evidence-Base for the Use of Mood Stabilizers and Antipsychotics in the Maintenance Treatment of Bipolar Disorder”

--
Allan H. Young, M.D., Ph.D.
 

4:15 p.m. Adjournment
4:30 p.m. -
6:00 p.m.
Poster Session
7:30 p.m. Mogens Schou Awards
Carnegie Museums of Pittsburgh
8:30 p.m.

Dinner
Carnegie Museums of Pittsburgh


DAY 3: SATURDAY, JUNE 18, 2005

7:45 a.m. Registration
Continental Breakfast
 
8:30 a.m. Concurrent Sessions III

S1. The First Episode
Boris Birmaher, M.D.
Benoit H. Mulsant, M.D.

S2. Woman’s Reproductive Health and Bipolar Disorder

Adele Viguera, M.D.
Katherine L. Wisner, M.D.

S3. Legal Issues
Robert M. Wettstein, M.D.

S4. What Psychiatry Residents Can Expect from NIMH-Sponsored Research Training
Joseph Calabrese, M.D.
Della M. Hann, Ph.D.

S5. Functioning: Definitions and Measurements
 K.N. Roy Chengappa, M.D.
Gordon Johnson, M.D.

Introductory Workshops on Psychosocial Therapy

S6A: Cognitive Behavioral Therapy
Noreen Reilly-Harrington, Ph.D.

S6B: Interpersonal and Social Rhythm Therapy
Debra Frankel, L.C.S.W.

S6C: Family Focused Therapy
Elizabeth L. George, Ph.D.
Dawn O. Taylor, Ph.D.

S6D: Psychoeducation
Eduard Vieta, M.D., Ph.D.

Advanced Workshops on Psychosocial Therapy

S7A: Cognitive Behavioral Therapy
Jan Scott, M.D., FRCPsych

S7B: Interpersonal and Social Rhythm Therapy
Holly Swartz, M.D.

S7C: Family Focused Therapy
David J. Miklowitz, Ph.D.

S7D: Psychoeducation
 Francesc Colom, Psy.D., M.Sc.,Ph.D.                                          Top


10:15 a.m.

Break
 

10:30 a.m.

Symposium V
 Diagnosis and Treatment: An International Perspective
 Chair: Mark S. Bauer, M.D

"Diagnosis and Treatment: A View from the Antipodes"
 --Philip Mitchell, M.D., FRANZCP, FRCPsych
"Hospitalization of Patients with Bipolar Disorders: A National Survey in Italy"
--Giovanni de Girolamo, M.D.

"Current Status of Care, Education, and Research in Brazil"
 Valentim Gentil, M.D., Ph.D.
 
12:00 p.m. Lunch (on your own)
 
1:00 p.m. Symposium VI
Advocacy/Research Forum: What Questions Do Patients Want Answered and How Can We Study Them?
Chair: Ellen Frank, Ph.D.

Adriano Camargo
Lydia Lewis
Atul Pande, M.D., FRCPC
Mauricio Tohen, M.D., Dr. PH
Eduard Vieta, M.D., Ph.D.
 
3:00 p.m. Concurrent Sessions IV

Lilly Fellows Forum

Meet the Doctors
1. David Axelson, M.D.
2. Andrea Fagiolini, M.D.
3. David J. Miklowitz, Ph.D.
4. Michael E. Thase, M.D.


4:15 p.m.

Adjournment

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