Stanley Center for the Innovative Treatment of Bipolar Disorder

FIFTH INTERNATIONAL CONFERENCE 
ON BIPOLAR DISORDER



Introduction

Proceedings

Bipolar Conferences Home

Biographical Sketches of Course Directors and Presenting Faculty (M - Z)

HUSSEINI K. MANJI, M.D., F.R.C.P.C.
Chief, Laboratory of Molecular Pathophysiology
National Institute of Mental Health
Bethesda, Maryland

Husseini K. Manji, M.D. is Chief, Laboratory of Molecular Pathophysiology, NIMH. Dr. Manji received his B.S. (Biochemistry) and M.D. from the University of British Columbia. Following psychiatry residency training, he subsequently completed fellowship training in psychopharmacology at the NIMH and undertook extensive additional training in Cellular and Molecular Biology at the NIDDK. The major focus of his ongoing research is the investigation of disease- and treatment-induced changes in gene and protein expression profiles that regulate neuroplasticity and cellular resilience in mood disorders. In broad terms, his laboratories’ scientific goals are to capitalize upon recent insights into our understanding of the signaling pathways mediating the effects of mood stabilizers, in order to understand the pathophysiology of severe mood disorders and to develop improved therapeutics. He has received ongoing research funding from the NIH, Private Foundations, and pharmaceutical industry for his work on signaling pathways, gene expression and new medication development for severe mood disorders.

Dr. Manji is a previous recipient of the A. E. Bennett Award for Neuropsychiatric Research, the 1999 Ziskind-Somerfeld Award for Neuropsychiatric Research, the 1999 NARSAD Mood Disorders Prize (Nola Maddox Falcone Prize), the NIMH award for excellence in clinical care and research, the 2002 NIMH Mentor of the year award, the NARSAD Independent Investigator Award, the Canadian Association of Professors in Psychiatry Award, and a Visiting Professor lectureship to the Salpetreire Hospital, Paris. He has published extensively on the molecular and cellular mechanisms of action of mood-stabilizing agents, and has edited a book on the mechanisms of action of antibipolar treatments.

He is a councilor for the Collegium Internationale neuro-psychopharmacologicum (CINP), a member of both the Canadian College of Neuropsychopharmacology and the American College of Neuropsychopharmacology (ACNP), and co-chair on the use of animals in psychopharmacology Committee of the ACNP. He is chair of the ACNP Task Force on Medication Development, NIMH Bipolar Initiative Scientific Advisory Board, is a member of the National Alliance for Research in Schizophrenia and Affective Disorders (NARSAD) Scientific Advisory Committee, National Alliance for the Mentally Ill (NAMI) Center on Practice & Research Advisory Committee, the Child and Adolescent Bipolar Foundation Professional Advisory Council, the Scientific Advisory Board of the Juvenile Bipolar Research Foundation and the Stanley Medical Research Institute Scientific Advisory Board. Dr. Manji has also served as a member of the National Board of Medical Examiners Behavioral Science Test Committee, and the USMLE Step 1 Test Material Development Committee for Behavioral Science, and is the Director of the NIH Foundation for the Advanced Education in the Sciences Graduate Course in the Neurobiology of Mental Illness, and co-chair, of the preclinical models workgroup of the NIMH Strategic Plan for mood disorders. Dr. Manji is currently editor of Neuroscience Perspectives, Biological Psychiatry, associate editor of the journal Bipolar Disorders, and sits on the Editorial Board of the official journal of the CINP.


LAUREN B. MARANGELL, M.D.
Brown Foundation Professor of Psychopharmacology
of Mood Disorders
Department of Psychiatry
Baylor College of Medicine
Houston, Texas

Lauren B. Marangell, MD, graduated from Baylor College of Medicine in 1987 and completed her internship, residency, and chief residency at Albert Einstein College of Medicine/Montefiore Medical Center in New York. She then spent three years at the National Institute of Mental Health, as a Fellow and Senior Staff Fellow, specializing in clinical research, psychopharmacology and mood disorders.

In 1994, Dr. Marangell joined the faculty of Baylor College of Medicine, where she is Director of Clinical Psychopharmacology, and Director of Mood Disorders Research in the Department of Psychiatry. She was recently appointed as the Brown Foundation Endowed Chair in Psychopharmacology. She has received numerous awards including the Laughlin Fellowship of the American College of Psychiatrists, the Young Investigators Award from the National Alliance for Research in Schizophrenia and Affective Disorders, the Exemplary Psychiatrist Award from the National Alliance for the Mentally Ill, and the McKnight Neuroscience of Brain Disorders Award

In addition to contributing numerous articles to the scientific literature, she is lead author of the Concise Guide to Psychopharmacology, published by The American Psychiatric Press Inc., in 2002.


DAVID MIKLOWITZ, Ph.D.
Professor of Psychology
University of Colorado
Boulder, Colorado

David Miklowitz, PhD, did his undergraduate work at Brandeis University and his doctoral (1979 to 1985) and postdoctoral work (1985 to 1988) at UCLA. He has been on the psychology faculty at the University of Colorado in Boulder since 1989. His research focuses on family environmental factors and family psychoeducational treatments for adult-onset and childhood-onset bipolar disorder.

Dr. Miklowitz has received the Joseph Gengerelli Dissertation Award from UCLA (1986), Young Investigator Awards from the International Congress on Schizophrenia Research (1987) and the National Alliance for Research on Schizophrenia and Depression (NARSAD; 1987), a Research Faculty Award from the University of Colorado (1998), and a Distinguished Investigator Award from NARSAD (2001). He also has received funding for his research from the National Institute for Mental Health and the John D. and Catherine T. MacArthur Foundation.

Dr. Miklowitz has published over 100 research articles and book chapters on bipolar disorder and schizophrenia. His articles have appeared in the Archives of General Psychiatry, the British Journal of Psychiatry, the Journal of Nervous and Mental Disease, Biological Psychiatry, the Journal of Consulting and Clinical Psychology, and the Journal of Abnormal Psychology. His book with Michael Goldstein, Bipolar Disorder: A Family-Focused Treatment Approach (Guilford), won the 1998 Outstanding Research Publication Award from the American Association of Marital and Family Therapy. His latest book, also with Guilford, is titled The Bipolar Disorder Survival Guide.


PHILIP MITCHELL M.B., B.S., M.D., F.R.A.N.Z.C.P., F.R.C.PSYCH.
Professor and Head, School of Psychiatry
University of New South Wales
Sydney, Australia

Philip Mitchell was appointed as Professor in the School of Psychiatry at the University of New South Wales (UNSW) in January, 1999 and then as Head of School in May, 2002.

Professor Mitchell graduated with first-class honours in Medicine from the University of Sydney in 1977. He received his MD by research from UNSW in 1991 for his studies on the neuroendocrinology of depression.

After working at Royal Prince Alfred Hospital in Sydney as a Professorial Intern, then SRMO, Professor Mitchell commenced postgraduate training in Psychiatry at the Prince of Wales and Prince Henry Hospitals in 1979. He continued his professional training in psychiatry in London from 1981 to 1983, working initially at St Georges’ Hospital then the Bethlem Royal and Maudsley Hospitals. It was while working in the UK that he first developed his research interests in mood disorders. On returning to Sydney in late 1983, he first worked as a Clinical Fellow in Psychiatry at Westmead Hospital. He became a Fellow of the Royal Australian and New Zealand College of Psychiatrists (RANZCP) in 1986 and a Fellow of the Royal College of Psychiatrists in 1996.

In 1985 he was offered the position of lecturer in the School of Psychiatry at UNSW, being subsequently promoted to Senior Lecturer in 1989 and Associated Professor in 1993. In 1993 he worked for six months as a Guest Researcher in Psychopharmacology at the National Institute of Mental Health in Bethesda, Maryland, USA. He was appointed as an honorary Senior Principal Research Fellow at the Garvan Institute of Medical Research in Sydney in 2001. In 2002 he was awarded the Organon Senior Research Award of the RANZCP.

Professor Mitchell’s major research interests are in the molecular genetics of bipolar disorder, pharmacological and psychological treatments of bipolar disorder and depression, phenomenological and epidemiological aspects of bipolar disorder, and transcranial magnetic stimulation as a treatment for depression and other psychiatric illnesses. He is a member of an NHMRC-funded program grant team studying depression and bipolar disorder.

Professor Mitchell has published (in conjunction with colleagues) over 250 papers or chapters on these topics. He is supervisor or co-supervisor of three doctoral students, and is on the editorial boards of ‘Psychiatric Genetics’ and the ‘World Journal of Biological Psychiatry’.

Professor Mitchell is currently President of the Australasian Society for Psychiatric Research, an associate member of the Australian Drug Evaluation Committee (ADEC), and serves on the Research Committee of the Australian Rotary Health Research Fund. He is also a member of the Chapter Professional Advisors Committee, National Depressive and Manic Depressive Association (U.S./international).


PAOLO LUCIO MORSELLI, M.D.
Vice President Fondazione IDEA
Vice-President ISBD
and Secretary General of GAMIAN-Europe
Milan, Italy

Paolo Lucio Morselli graduated with honors in Medicine (1961) and specialized in Psychiatry (1965 cum laude) from the University of Milan, Milan, Italy. He then spent two years, as a Fullbright-Hays Fellow at the Department of Biochemical Pharmacology, Medical College of Virginia, Richmond, Virginia, USA. In 1968 Professor Morselli returned to Italy, where he was appointed Head of the Clinical Pharmacology Unit at the Mario Negri Institute, Milan. From 1976–1994, he held a variety of professional posts at Synthélabo Pharmaceutical, Paris, France, including Executive Director of Clinical Research, Director General for Medical Affairs and Corporate Vice-President for Clinical Research and Development. He retired in 1994. He has received several awards for his work including the “Ambrogino d’oro” from the City of Milano (1972), the “ASPET-ILAE Research Award” (1978), the “Ambassador for Epilepsy Award” (1979), and the “Prix-Galien Award” ( Paris-1992). He has been quoted in Marquis “Who is Who in the World” (1990, 1992 and 2003 eds.). Professor Morselli is a member of several professional and medical societies, and is on the Editorial Boards of 13 international scientific journals. He has published more than 480 scientific articles and 20 specialized monographs. Professor Morselli has been “Visiting Professor” at several French Universities (1980–1992) and at Universidad Autonoma de Barcelona , España (1991-2000), “Associated Scientist” at “Institut Philippe Pinel de Montréal,” Canada (1994) and “Professore a contratto” at the Department of Psychiatry of the University of Pisa, Italy (2000-2002). Professor Morselli currently serves, on a volunteer “pro bono basis” in two Advocacy Organization operating in the Mental Health field: as Vice-President of Fondazione-IDEA in Milan, Italy (1997–present), and as Secretary General of GAMIAN-Europe (1998–present) where he is also a “charter member”. He is also serves as Vice-President for ISBD (2001- present).

Present major interests are: social and therapeutic aspects of mood disorders and more specifically Bipolar Disorder; the problems linked to stigma and prejudice associated with unipolar depression, Bipolar Disorder and other mental illnesses; and the role of advocacy associations for mental illnesses in the long term management of the psychiatric patient.


BRUNO MÜLLER-OERLINGHAUSEN, Dr.med.
Professor em. of Clinical Psychopharmacology
Freie Universität Berlin
Chairman of the Drug Commission of the German Medical Association
Berlin, Germany

Bruno Müller-Oerlinghausen was born in 1936 in Berlin. He obtained his training in medicine at the universities of Göttingen, Munich, Francfort/M., Freiburg, and Berlin (West). 1964 to 1969 he underwent a postgraduate training in pharmacology and toxicology at the Department of Pharmacology, University of Goettingen, and qualified as a lecturer in pharmacology and toxicology with a thesis on “Hormonal influence on mechanisms of hepatic detoxification”. 1969 to 1971 he was assigned to the Department of Medical Sciences (Ministry of Public Health) in Bangkok (Thailand) by the government of the Federal Republic of Germany as an expert in pharmacology. He built up a pharmacological research lab and trained the Thai staff in methods to investigate the pharmacology of old-style herbal medicine. In 1971 he entered the Department of Psychiatry, Freie Universität Berlin, for additional training in clinical psychiatry, and in 1974 he was appointed as Chief Scientist of the Lithium Clinic Berlin, and at the same time promoted to Professor of Clinical Psychopharmacology and Chief of the Laboratory of Clinical Psychopharmacology. For 27 years he was editor-in-chief of Pharmacopsychiatry, and he is associate editor of many other journals, such as Bipolar Disorders, Journal of Psychiatry and Neuroscience or Drug Research. 1983 to 1987 he was elected as president of AGNP (Association for Neuropharmacology of the German speaking countries), 1982 to 1988 he served as Councillor of the Executive Board of CINP. Since 1994 he is the acting chairman of the Drug Commission of the German Medical Association.

His scientific interests were mainly related to the clinical pharmacology of antidepressants, neuroleptics and particularly lithium salts in humans. Recent work focused on long-term effects of lithium salts with special regard to its serotonergic action including anti-aggressive and antisuicidal effects; serotonergic mechanisms in patients with affective disorders; genetic studies in depression and in clozapine-induced agranulocytosis.


MICHAEL W. OTTO, PH.D.
Director, Cognitive-Behavior Therapy Program
Massachusetts General Hospital (MGH)
Associate Professor of Psychology
Department of Psychiatry, Harvard Medical School
Boston, Massachusetts

Dr. Otto specializes in the cognitive-behavioral treatment of anxiety and mood disorders, and has developed clinical-research programs at MGH for the treatment of panic disorder, posttraumatic stress disorder, social phobia, bipolar disorder, psychotic disorders, substance dependence, and medication discontinuation in patients with panic disorder. Dr. Otto's research activities are closely tied to his clinical interests and target investigations of the etiology and treatment of anxiety, affective, and substance-use disorders. Of particular interest to Dr. Otto is the development and testing of new treatments, including the combination of pharmacologic and cognitive-behavioral strategies for treatment-refractory and substance abusing patients, and the modification of treatment packages for novel populations (e.g., Cambodian refugees). He has published over 150 articles, book chapters, and books spanning these research interests. His books include Challenges in Clinical Practice: Pharmacologic and Psychosocial Strategies, co-edited with Drs. Pollack and Rosenbaum, and the Stopping Anxiety Medication treatment manuals for patients and therapists. Dr. Otto is a fellow of the American Psychological Association, directs fellowship and internship training in cognitive-behavior therapy at MGH, and has been a regular provider of continuing education and continuing medical education workshops across the United States and abroad. He also serves as a section editor for Cognitive and Behavioral Practice, and on the editorial boards of Behavior Research and Therapy, Clinical Psychology: Science and Practice, Journal of Anxiety Disorders, Journal Watch in Psychiatry, and Psychotherapy and Psychosomatics.


PAMELA B. PEELE, Ph.D.
Assistant Professor of Health Economics
Graduate School of Public Health
University of Pittsburgh
Pittsburgh, Pennsylvania

Dr. Pamela Peele is an Associate Professor of Health Economics in Health Policy & Management and Psychiatry. She received her undergraduate training in economics at Roanoke College in Salem, Virginia and her Masters and Ph.D. in economics from Virginia Polytechnic Institute and State University. Her formal economics training is in industrial organization and game theory. She is a Registered Electroencephalographic Technologist. She is Core Faculty at the Center for Research on Health Care at the University of Pittsburgh. She serves on the Advisory Board for the Center for Injury Research and Control at the University of Pittsburgh and on the Advisory Board for Business Administration and Economics at Roanoke College.

Dr. Peele’s research focuses on work and health. She has multiple projects and publications related to financing and delivery of mental health care as well as occupational research focused on the health of workers, including the influence of depression on occupational injury. Her work includes partnerships with public and private corporations and has been recognized by the Association of Schools of Public Health as outstanding collaboration between academia and practice.

Dr. Peele teaches a graduate course in health economics in the Graduate School of Public Health that applies game theory to health care markets. She is the recipient of several teaching awards. She also lectures frequently on medical, occupational, and mental health care financing. She is ad hoc reviewer for the National Science Foundation, the Whitaker Foundation, and the National Institute of Occupational Safety and Health. She presents annual workshops in game theory for the National Math/Science Foundation aimed at keeping 12-15 year old girls interested in math and science. She is a member of various professional organizations, including the Committee on the Status of Women in the Economics Profession and is an elected member of Delta Omega honor society in Public Health. She is listed in Who’s Who in America.


NOREEN A. REILLY-HARRINGTON, Ph.D.
Instructor in Psychology
Harvard Medical School
Clinical Assistant in Psychology
Massachusetts General Hospital
Department of Psychiatry
Boston, Massachusetts

Noreen A. Reilly-Harrington, Ph.D. is an Instructor in Psychology at Harvard Medical School and is on the staff of the Harvard Bipolar Research Program at Massachusetts General Hospital. She is a graduate of University of Pennsylvania and Temple University and completed her internship and post-doctoral fellowship at Massachusetts General Hospital and Harvard Medical School. Dr. Reilly-Harrington is a Founding Fellow of the Academy of Cognitive Therapy and has received research awards from the Society for Research in Psychopathology, the Association for the Advancement of Behavior Therapy, and Massachusetts General Hospital for her work examining the role of life stress and cognition on the course of bipolar mood disorders. She has lectured both nationally and internationally on the topic of cognitive therapy for bipolar disorder and has recently co-authored a book entitled “Bipolar Disorder: A Cognitive Therapy Approach” published by the American Psychological Association. She currently serves as a Psychosocial Pathway Leader and Clinical/Scientific Coordinator for the National Institute of Mental Health's Systematic Treatment Enhancement Program for Bipolar Disorder, the largest study of bipolar disorder ever conducted. Dr. Reilly-Harrington is the recipient of a NIMH Small Business Innovative Research grant designed to improve rater reliability through the use of innovative technology. She is also involved in studies examining neuropsychological functioning in bipolar disorder and cognitive-behavioral treatment for rapid cycling bipolar disorder.


ALESSANDRO ROTONDO, M.D.
Researcher
Department of Psychiatry, Neurobiology, Pharmacology, and Biotechnology
University of Pisa
Pisa, Italy

Dr. Rotondo received his medical training in Italy at the University of Pisa. He completed his psychiatric residency at the Department of Psychiatry, Neurobiology, Pharmacology, and Biotechnology (DPNPB) of the University of Pisa and his training in neurogenetics at the Laboratory of Neurogenetics of the National Institute on Alcohol Abuse and Alcoholism/National Institutes of Health, Rockville, MD. Since 1997 he has been on the faculty at the University of Pisa, in the DPNPB. Currently he is a researcher at the DPNPB.

Dr. Rotondo has done research in neurochemistry of neuroreceptors (particularly serotonin) and their involvement in the pathophysiology of mood and anxiety disorders. In the last eight years, his research has focused on genetic association studies, mainly on the association of candidate genes with mood disorders, eating disorders, and self-harm behavior. He is the author of about thirty publications in international journals.

Dr. Rotondo is the recipient of research project grants from the Italian government on the genetics of mood disorders and eating disorders, as well as on the pharmacogenetics of antidepressant and atypical antipsychotics. He also participates in international collaborative studies on the genetics of eating disorders and panic disorder.


GARY S. SACHS, M.D.
Associate Professor in Psychiatry
Harvard Medical School
Director, Bipolar Mood Disorder Program
Massachusetts General Hospital

Gary S. Sachs, M.D., is Associate Professor in Psychiatry at Harvard Medical School; Clinical Assistant in Psychiatry and Director, Bipolar Mood Disorder Program, at Massachusetts General Hospital; Director, Harvard Bipolar Research Program; and Director, Partners Bipolar Treatment Center. Dr. Sachs earned his medical degree at the University of Maryland School of Medicine. He interned in family practice and psychiatry at University of Maryland Hospital in Baltimore, was a resident in psychiatry and Chief Resident, Acute Psychiatry Service, at Massachusetts General Hospital in Boston.

Dr. Sachs is the Principal Investigator of the NIMH Systematic Treatment Enhancement Program for Bipolar Disorder. He serves on the scientific advisory board of the National Depression and Manic Depression Association and is Co-editor-in-chief of Clinical Approaches to Bipolar Disorder and on numerous editorial boards. Dr. Sachs has authored over 150 articles, abstracts, books, reviews, and book chapters.


JAN SCOTT, M.D., FRCPsych.
Professor of Psychological Treatments Research
Institute of Psychiatry, Decrespigny Park
London, United Kingdom

Jan Scott, M.D., FRCPsych is now Professor of Psychological Treatments Research, at the Institute of Psychiatry in London. Her clinical work is focused on the treatment of individuals with chronic and severe affective disorders. Her research focuses on development of psychobiosocial models of mood disorders and exploring the benefits of combined pharmacological and psychological treatment strategies. Professor Scott is the principal investigator on the Medical Research Council multi-centre randomized controlled trial of cognitive therapy for bipolar affective disorders. She has over 250 publications in psychiatry and a number of books including one written for individuals with bipolar disorder called ‘Overcoming Mood Swings’.

Previous clinical posts include training in cognitive therapy with Professor Aaron T. Beck in Philadelphia, USA. She was awarded the Royal College of Psychiatrists Travelling Fellowship to undertake clinical and research training in Madison, Wisconsin and Johns Hopkins University in Baltimore. Professor Scott is a member of a number of national and international committees; is a former Sub-Dean of the Royal College of Psychiatrists, UK; the immediate Past President of the British Association for Behavioural & Cognitive Psychotherapy; an assistant editor of the British Journal of Psychiatry, the Journal of Mental Health and Psychotherapy and Psychosomatics; and the vice-chair of the Mental Health and Neurosciences Board of the Medical research Council in the UK. She is a professional adviser to the Manic Depression Fellowship of Britain and was made a Distinguished Founding Fellow of the International Academy of Cognitive Therapy (one of 8 individuals worldwide).


KENNETH I. SHULMAN, M.D.
Professor, Department of Psychiatry
Sunnybrook & Women’s College Health Sciences Centre
University of Toronto
Toronto, Ontario

Dr. Shulman graduated from the Faculty of Medicine, University of Toronto in 1973 and did postgraduate training in Psychiatry at the University of Toronto. He then went on to do specialty training in Geriatric Psychiatry in London, England. Since 1978, he has been based at Sunnybrook & Women’s in Toronto where he has been involved in the development of a comprehensive geriatric psychiatry service and academic program. In 1990, he completed a Master of Science in Health Policy and Management at the Harvard School of Public Health.

Dr. Shulman was formerly the Director of the Division of Geriatric Psychiatry at the University of Toronto and Foundation Director of the Interdepartmental Division of Geriatrics for the Faculty of Medicine. For ten years he served as Psychiatrist-in-Chief at Sunnybrook & Women’s and Vice-Chair, Clinical Affairs of the University of Toronto, Department of Psychiatry. In 2001 he joined the Board of Directors of the International Psychogeriatric Association. He is the inaugural recipient of the Richard Lewar Chair in Geriatric Psychiatry at Sunnybrook & Women’s, University of Toronto.

Academic interests include mania and bipolarity in old age; the clock drawing test and brief cognitive screening; mental health policy; and testamentary capacity.


GREGORY SIMON, M.D., M.P.H.
Senior Investigator
Center for Health Studies
Group Health Cooperative
Seattle, Washington

Dr. Simon received his MD degree from the University of North Carolina followed by residency training in internal medicine at the University of Washington, residency training in psychiatry at Massachusetts General Hospital, and fellowship training in the Robert Wood Johnson Clinical Scholars Program at the University of Washington. Since 1990 he has been an investigator at the Center for Health Studies of Group Health Cooperative and has practiced adult Psychiatry in Group Health’s Behavioral Health Service.

Dr. Simon’s research has focused on the epidemiology and management of mood disorders in both primary care and psychiatric practice. Specific research topics have included: epidemiology of mental disorders in primary care, economic burden of mood and anxiety disorders, interventions to improve depression management in primary care, cost-effectiveness of treatments for mood disorders, psychotherapy for depression and bipolar disorder, relative effectiveness of different antidepressant and mood stabilizer drugs, and suicide risk in depression and bipolar disorder.

Dr. Simon has published approximately 150 scientific articles and book chapters, and serves on the editorial boards of several psychiatric and general medical journals. He also serves on the national advisory board of the Depression and Bipolar Support Alliance. In 2002 he received the Senior Scholar Award for Health Services Research from the American Psychiatric Association.

Dr. Simon continues to practice outpatient psychiatry approximately half-time with a focus on treatment-resistant depression and bipolar disorder.


HOLLY A. SWARTZ, M.D.
Assistant Professor of Psychiatry
University of Pittsburgh School of Medicine
Depression and Manic-Depression Prevention Program
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania

Dr. Swartz received a bachelor’s degree from Harvard University in Cambridge, Massachusetts and her medical degree from the Albert Einstein College of Medicine in the Bronx, New York. She completed her psychiatric residency at Payne Whitney Clinic-New York Hospital in New York City, and she joined the faculty of the Department of Psychiatry at the University of Pittsburgh Medical School in 1997. She is currently an attending psychiatrist at the Depression and Manic-Depression Prevention Program of Western Psychiatric Institute and Clinic and a recipient of a Mentored Patient-Oriented Research Career Development grant from the National Institute of Mental Health.

Dr. Swartz’s research focuses on the development and evaluation of psychosocial interventions for the treatment of mood disorder. She is specifically interested in optimizing interventions for women with mood disorders and adapting psychotherapies for difficult-to-treat populations. She is currently conducting a trial of brief psychotherapy for depressed mothers whose children also suffer from a psychiatric disorder. She is a co-investigator for the Maintenance Therapies in Bipolar Disorder study at the University of Pittsburgh and has a longstanding interest in the role of psychotherapy in the management of bipolar disorder.

Dr. Swartz has been the recipient of a Reader’s Digest Research Fellowship from Cornell University Medical College and a Junior Faculty Scholar Award from the University of Pittsburgh Department of Psychiatry. She received a Golden Apple Award nomination for her excellence in teaching psychiatry residents, and a 2003 NCDEU New Investigator Award. Dr. Swartz is a member of a number of professional societies, including the American Psychiatric Association, the Society for Psychotherapy Research, the International Society for Interpersonal Psychotherapy, and the International Society for Bipolar Disorders. She serves as an ad hoc reviewer for Bipolar Disorders. Dr. Swartz has presented her work at numerous local, national, and international workshops, conferences and scientific meetings.


MICHAEL E. THASE, M.D.
Professor of Psychiatry
University of Pittsburgh School of Medicine
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania

Michael E. Thase, M.D., is a Professor of Psychiatry at the University of Pittsburgh School of Medicine and the Western Psychiatric Institute and Clinic. He is an active clinical investigator, whose research focuses on the assessment and treatment of mood disorders, including the correlates of differential response to various treatments for depression. A 1979 graduate of the Ohio State University College of Medicine, Dr. Thase has directed the Depression Treatment and Research Program at the University of Pittsburgh since its inception in 1987 and is now the Chief of Adult Academic Psychiatry. A Fellow of the American Psychiatric Association, Dr. Thase has authored or co-authored over 350 scientific articles and book chapters, as well as 8 books.


MAURICIO TOHEN, M.D., Dr. P.H.
Lilly Clinical Research Fellow, Lilly Research Laboratories
Eli Lilly and Company
Associate Clinical Professor Psychiatry
Harvard Medical School
Indianapolis, Indiana

Mauricio Tohen, M.D., Dr.P.H., graduated as a doctor of medicine from the National University of Mexico in 1976 and as a doctor of public health (epidemiology) from Harvard University in 1988. His postdoctoral training included a residency in psychiatry at the University of Toronto (1979 - 1982) and a fellowship at McLean Hospital, Harvard Medical School (1982 - 1985). From 1988 to 1997, he was clinical director of the Bipolar and Psychotic Disorder Program at McLean Hospital. In 1997, he joined Lilly Research Laboratories where he is currently a Lilly Clinical Research Fellow and Medical Director of the Zyprexa Product Team. He is also an Associate Clinical Professor of Psychiatry at Harvard Medical School.

He received a National Service Award in Psychiatric Epidemiology from NIMH and Harvard University. He also received a FIRST award from NIMH, the Pope Award from McLean Hospital, and a NARSAD Young Investigator Award. Dr. Tohen’s research, supported by grants from NIMH and the pharmaceutical industry, has focused on the epidemiology, outcome, and treatment of bipolar disorder.

He has served on the Council on Research and the committee on Health Services Research of the American Psychiatric Association. He has also served in the Epidemiology & Genetics and the Clinical Centers and Special Projects Review committees at NIMH. Dr. Tohen has over 100 publications. He co-edited two books, Psychiatric Epidemiology (1995) and Mood Disorders Across the Life Span (1996). He also edited the book Comorbidity in Affective Disorders (1999).


LEONARDO TONDO, M.D.
Department of Psychology
University of Cagliari
Director
Centro Lucio Bini
Cagliari, Italy

Leonardo Tondo, M.D., M.S., completed his medical education at the University of Rome, graduating summa cum laude. In 1977, he became the founding director of the Centro Lucio Bini in Cagliari, Sardinia, that was included in the Stanley Medical Research Institute Research Program in 1998. From 1980 to 2000, he was an assistant professor at the University of Cagliari, and since 2000, he has been Associate Professor in General Psychology at the Department of Psychology of Cagliari University. In 1980, Dr. Tondo was a visiting scientist at Johns Hopkins University. In 1983, he was a lecturer at the University of Pennsylvania; and in 1986 he was a researcher at UCLA. Since 1994, he has been associated with the Department of Psychiatry at Harvard University and the McLean Hospital. His main research topics are the course of bipolar disorders, treatment with lithium, and medical prevention of suicide. He has received research awards from NARSAD and the Stanley Foundation since 1995. In 2003, he received a Master of Science in Epidemiology from the Harvard School of Public Health. Dr. Tondo is the author of more than one hundred international publications.


PER VESTERGAARD, Dr.Med.Sc.
Professor of Psychiatry Aarhus University Aarhus University Psychiatric Hospital Risskov, Denmark

Dr. Vestergaard is Professor of Clinical Psychiatry of Aarhus University, Denmark. He is also Director of Clinical Research, and Chief of Clinical Outpatient Services at the University Psychiatric Hospital. He founded the Mood Disorder Research Unit and the Lithium Clinic of the Aarhus Psychiatric Hospital. He has conducted research and published articles on the clinical pharmacology of lithium, on the treatment efficacy of old and new antidepressant drugs, on affective disorders in general and bipolar disorder in particular. He was a co-founder of the Danish University Antidepressant Group (DUAG). He has published textbooks on psychiatry and psychopharmacology and is an editorial consultant on several psychiatric journals. Dr. Vestergaard is a recipient of Stanley Institute Grants.


EDUARD VIETA, M.D., PH.D.
Director of the Bipolar Disorder Program
Hospital Clinic
University of Barcelona
Barcelona, Spain

Eduard Vieta is currently Director of Research and Director of the Bipolar Disorders Program of the Hospital Clinic at the University of Barcelona, Spain. He also serves as Postgraduate Professor of Psychopharmacology and Affective Disorders at the University. He has authored over 100 original articles, 21 book chapters and 9 complete books on bipolar disorder.


ADELE C. VIGUERA, M.D.
Assistant Professor of Psychiatry
Harvard Medical School
Associate Director of the Perinatal and Reproductive Psychiatry Program
Massachusetts General Hospital
Boston, Massachusetts

Adele C. Viguera, M.D., is the associate director of the Perinatal and Reproductive Psychiatry Program at Massachusetts General Hospital and an Assistant Professor of Psychiatry at Harvard Medical School in Boston, Massachusetts. Dr. Viguera received her MD from Dartmouth Medical School in Hanover, New Hampshire, and served her internship and residency at Massachusetts General Hospital and McLean Hospital in Belmont, Massachusetts.

The recipient of several honors and awards, Dr. Viguera is a recent recipient of an NIMH sponsored K23 Mentored Patient-Oriented Research Career Development Award as well as a NARSAD Young Investigators Award for her project on neonatal outcome following exposure to Lithium: What Happens to Lithium Babies? Her current research interests include the course and treatment of bipolar mood disorders during pregnancy and the postpartum period and the effects of prenatal lithium exposure on infant development.

Dr. Viguera’s research, teaching and clinical activities focus on women’s mental health, specifically psychiatric disorders across the female reproductive life-cycle. Her area of particular interest are major mood disorders associated with pregnancy and the postpartum period. Dr. Viguera’s additional clinical activities include outpatient evaluation, consultation and clinical follow-up in both the Perinatal & Reproductive Psychiatry Program and the Obstetrics and Gynecology Outpatient Department at the Massachusetts General Hospital. She performs diagnostic and psychopharmacologic consultation on pregnant and postpartum women with major mood disorders. Her work has been published in a number of scientific journals and books.


ROBERT M. WETTSTEIN, M.D.
Clinical Professor of Psychiatry
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania

Dr. Wettstein is in the private practice of psychiatry, with an emphasis on legal and ethical practice issues. He is a consultant to the state licensing boards in medicine, psychology, nursing, dentistry, chiropractic, and law, and evaluates impaired professionals. He also conducts independent examinations regarding disability, workers compensation, and criminal responsibility.

Between 1984 and 1996, Dr. Wettstein was on the full-time faculty at WPIC, and was codirector of the Law and Psychiatry Program. He was involved in clinical consultations, treatment, and research activities in the law and psychiatry area. In 1996, he was awarded the “Golden Apple” award for excellence in teaching by the residents of WPIC.

Dr. Wettstein was Editor of the quarterly journal Behavioral Sciences and the Law until 1996. He is coauthor with Barbara Weiner, Esq. of Legal Issues in Mental Health Care. His edited volume, Treatment of Offenders with Mental Disorders, was published in 1998. He is also author of many other publications on legal and ethical issues in mental health care.

He is the President-Elect of the American Academy of Psychiatry and the Law.


LAKSHMI N. YATHAM, M.B., F.R.C.P.C.
Michael Smith Foundation Senior Scholar Associate Professor of Psychiatry
Director, Mood Disorders
Clinical Research Unit
University of British Columbia
Vancouver, British Columbia, Canada

Lakshmi N. Yatham, MB, FRCPC, is Associate Professor of Psychiatry and Director of the Mood Disorders Clinical Research Unit at the University of British Columbia in Vancouver. His major areas of research interest include neurobiology and treatment of bipolar disorder and major depression. Dr. Yatham is a recipient of the Michael Smith Foundation Senior Scholar Award, and his work has been funded by a number of peer-reviewed funding agencies such as the Canadian Institutes of Health Research (CIHR), Canadian Psychiatric Research Foundation, Stanley Foundation, and National Alliance for Research on Schizophrenia and Depression, USA. Dr. Yatham leads a Canadian consortium on bipolar disorder, which is currently pursuing development and testing of new and innovative treatments for bipolar disorder under his direction with substantial funding from CIHR.

Dr. Yatham co-led the development of Canadian guidelines for treatment of bipolar disorder. He is Chair of the bipolar group of the Canadian Network for Mood and Anxiety Treatments (CANMAT), and is actively involved at a national and international level in continuing medical education and public education on diagnosis and treatment of bipolar disorder for psychiatrists, family physicians, and the general public. Dr. Yatham is the Secretary/Treasurer for International Society on Bipolar Disorders and he is on the editorial boards of a number of journals including Bipolar Disorders, Brain Pharmacology, and Human Psychopharmacology. He has published over 100 papers in peer-reviewed international journals and presented his research work at numerous international conferences.


ALLAN H. YOUNG, M.D., Ph.D.
Professor of Psychiatry
School of Neuroscience and Psychiatry
University of Newcastle
Royal Victoria Infirmary
Newcastle upon Tyne, United Kingdom

Professor Allan Young trained in medicine and thereafter psychiatry at the University of Edinburgh and held a Royal College of Physicians of Edinburgh training fellowship at the MRC Brain Metabolism Unit. Subsequently, he was a clinical lecturer at the University of Oxford and worked in the MRC Clinical Psychopharmacology Unit with Professor Philip Cowen before becoming Senior Lecturer and Honorary Consultant at the University of Newcastle.

Now Professor of General Psychiatry, Allan Young is also Director of both Psychiatry and the Stanley Research Centre at the University of Newcastle. He is a Council Member of the British Association for Psychopharmacology and Secretary of the Royal College of Psychiatrists’ Psychopharmacology Special Interest Group, and member of the Scientific Advisory Council of the Stanley Medical Research Institute.. He has published over 200 scientific publications on the etiology and treatment of psychiatric disorders, particularly mood disorders.

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