Stanley Center for the Innovative Treatment of Bipolar Disorder

FOURTH INTERNATIONAL CONFERENCE 
ON BIPOLAR DISORDER



Introduction

Proceedings

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Schedule

DAY 1: THURSDAY, JUNE 14, 2001

MORNING
 
7:45 a.m. Registration and Continental Breakfast
 
8:30 a.m. Overview
David J. Kupfer, M.D.
RealMedia  Audio  (Length:  7:54 min.)

Session I: "Updates and Goals"
Chair: David J. Kupfer, M.D.
 
8:45 a.m. Part I: "Updates on Pharmacotherapy and Neuroscience"

"Are There Core Neuropsychological Abnormalities in Bipolar Disorder?"
Guy Goodwin, M.D.
RealMedia  Audio  (Length:  30:54 min.)

"Update on Pharmacotherapy"
Paul E. Keck, M.D.
RealMedia  Audio  (Length:  36:52 min.)


9:55 a.m.
 
Break
10:10 a.m. Part II: "Update on Stanley Foundation Programs in Bipolar Disorder"

"Neuropathology"
Paul Harrison, M.D.
RealMedia  Audio  (Length:  31:07 min.)

"An Update on the Stanley Foundation Bipolar Network (SFBN)"
Robert M. Post, M.D.
RealMedia  Audio  (Length:  28:32 min.)


11:20 a.m.

Panel Discussion
RealMedia  Audio  (Length:  36:22 min.)
 
11:45 a.m. Lunch Provided
"Goals for NIMH Research in Bipolar Disorder"
Steven Hyman, M.D.
RealMedia  Audio  (Length:  47:13 min.)


AFTERNOON


Session II: "Child/Adolescent Bipolar Disorder"
Chair: Jules Angst, M.D.
 
1:00 p.m.

"Course and Outcome of Bipolar Disorder in Adolescents"
Boris Birmaher, M.D.
RealMedia  Audio  (Length:  22:34 min.)

"Diagnosis and Follow-up of a Prepubertal and Early Adolescent Bipolar Disorder Phenotype"
Barbara Geller, M.D.
RealMedia  Audio  (Length:  22:17 min.)  

"Bipolar Disorder: A Developmental and Psychoendocrine Perspective"
Ian M. Goodyer, M.D. F.Med.Sci.
RealMedia  Audio  (Length:  25:55 min.)

"Pharmacological Treatments of Children and Adolescents"
Robert A. Kowatch, M.D.
RealMedia  Audio  (Length:  20:02 min.)

"What Are the Risk Factors for an Early Development of Bipolar Disorder in Children?"
Catrien Reichart, M.D.
RealMedia  Audio  (Length:  21:56 min.)

 
Panel Discussion
Discussant: Martha Hellander
RealMedia  Audio  (Length:  45:47 min.)

3:45 p.m.
 
Break
4:00 p.m.

"Rapid Communications Session"
Moderator: Jair C. Soares, M.D.

"Using fMRI to Study Euthymic Bipolar Patients: Investigating Word Generation"
Dr. Vivienne Curtis/Paul J. Monks, M.B., BCHIR, MRCPSYCH
RealMedia  Audio  (Length:  17:16 min.)

"The Serotonin Transporter Protein Gene and Suicidal Behavior in Bipolar Disorder"
Emanuela Mundo, M.D.
RealMedia  Audio  (Length:  16:04 min.)

"Acute Tryptophan Depletion in First-degree Relatives of Bipolar Disorder Patients: Effects on Mood, Cognition, and Cortisol Release"
Sjacko Sobczak, M.Sc.
RealMedia  Audio  (Length:  11:14 min.)

"G-Proteins and Regulators of G-Protein Signaling in Neutrophils of Manic- depressive Patients: Effects of Mood Stabilizers"
Dietrich O. van Calker, Ph.D., M.D.
RealMedia  Audio  (Length:  11:06 min.)


5:00 p.m.

Adjournment

5:00 p.m.

Poster Session

7:00 p.m. -
9:00 p.m.
 
Reception
The Grand Concourse Restaurant

DAY 2: FRIDAY, JUNE 15, 2001


MORNING
 
7:45 a.m. Registration and Continental Breakfast
8:30 a.m. Overview
Michael E. Thase, M.D.
RealMedia  Audio  (Length:  4:21 min.)


Session III: "Multi-site Treatment Trials"
Chair: Michael E. Thase, M.D.
 

8:45 a.m.

"Principles for Efficacy Trials: The Example of VA Cooperative Study #430"
Mark S. Bauer, M.D.
RealMedia  Audio  (Length:  26:39 min.)

"STAR*D: An Effectiveness Trial for Major Depressive Disorder"
A. John Rush, M.D.
RealMedia  Audio  (Length:  40:11 min.)

"Design and Promise of NIMH Multicenter Effectiveness Trials"
Gary S. Sachs, M.D.
RealMedia  Audio  (Length:  45:01 min.)


10:45 a.m.

Break

11:00 a.m.
 

Panel Discussion
Discussants: Barry D. Lebowitz, M.D.,
Greg Simon, M.D.
RealMedia  Audio  (Length:  15:41 min.)

11:30 a.m.

Lunch (on your own)

12:30 p.m.

International Society for Bipolar Disorders Membership Meeting
Samuel A. Gershon, M.D. [audio and slides]
RealMedia  Audio  (Length:  55:27 min.)
1:00 p.m.

Interactive Sessions: Ask the Experts

1. "Impact of Anxiety Spectrum Comorbidities on Bipolar Disorder"
Giovanni B. Cassano, M.D.
[audio and slides]
RealMedia  Audio  (Length:  57:29 min.)

2. "Efficacy versus Effectiveness in Long-term Lithium Prophylaxis and Related Compliance Issues"
Per Vestergaard, Dr.Med.Sc.
[audio]
RealMedia  Audio  (Length:  58:10 min.)

3. "Treatment of Bipolar Disorder Patients in the Young and Middle Adult Years"
Paula J. Clayton, M.D.
[audio and slides]
RealMedia  Audio  (Length:  43:02 min.)

4. "Suicide: From a Historical Background to Modern Prevention"
Leonardo Tondo, M.D. [audio and slides]
RealMedia  Audio  (Length:  33:58 min.)

5.  "Antisuicidal Effect of Lithium"
Bruno M
üller-Oerlinghausen, Dr.med. [audio and slides]
RealMedia  Audio  (Length:  21:11 min.)

6. "Use of Industry Data"
Atul Pande, M.D. [audio and slides]
RealMedia  Audio  (Length:  45:53 min.)

7. "Studying Treatments of Bipolar Disorder in the Real World:  The NIMH STEP-BD Project"
Gary S. Sachs, M.D. and Michael E. Thase, M.D.
[audio]
RealMedia  Audio  (Length:  51:33 min.)


2:00 p.m.
 
Break

AFTERNOON

Session IV: "Regulatory Issues in Developing Drug Treatments for Bipolar Disorder"
Chair: Samuel A. Gershon, M.D.
 
2:15 p.m.

Introduction
RealMedia  Audio  (Length:  4:29 min.)

Jitschak Storosum, M.D.
Thomas P. Laughren, M.D.
Fouzia Laghrissi-Thode, M.D.
Earl L. Giller, Jr. M.D.
Alan Metz, M.D.
Willem A. Nolen, M.D., Ph.D.


3:45 p.m.
 

Panel Discussion
RealMedia  Audio  (Length:  27:01 min.)
 
4:15 p.m.

"Rapid Communications Session"
Moderator: Fouzia Laghrissi-Thode, M.D.

"Treatment Response as an Alternative Phenotype in Studies of Bipolar Disorder"
Martin Alda, M.D., FRCP(C)
RealMedia  Audio  (Length:  15:34 min.)

"Bipolar Rapid Cycling: Focus on Depression as Its Hallmark"
Joseph R. Calabrese, M.D.
RealMedia  Audio  (Length:  14:39 min.)  

"Pramipexole in Treatment-resistant Depression: A 16-Week Naturalistic Study"
Paolo Cassano, M.D.
RealMedia  Audio  (Length:  14 min.)

"Hidden Bipolarity in Early-onset versus Juvenile OCD"
Frederic J. Kochman, M.D.
RealMedia  Audio  (Length:  11:51 min.)

"Non-adherence with Mood Stabilizers: Prevalence, Predictors and Prognosis"
Jan Scott, M.D., FRCPsych
RealMedia  Audio  (Length:  14:20 min.)


5:15 p.m.

Adjournment

5:15 p.m.

Poster Session

7:00 p.m.

Cocktails
The Carnegie Museums of Pittsburgh

8:00 p.m.


Dinner
The Carnegie Museums of Pittsburgh
"Mogens Schou Awards":

Jules Angst, M.D.
Mogens Schou, M.D.
Vada and Ted Stanley

RealMedia  Audio  (Length:  29:31 min.)


DAY 3: SATURDAY, JUNE 16, 2001


MORNING
 
7:45 a.m. Registration and Continental Breakfast
8:30 a.m. Overview
Ellen Frank, Ph.D.
RealMedia  Audio  (Length:  7:50 min.)


Session V: "International Advocacy Forum"
Chairs: Lydia Lewis and Paolo Lucio Morselli, M.D.
 

8:45 a.m.

"Introductory Remarks"
Paolo Lucio Morselli, M.D.
IDEA
Italy
RealMedia  Audio  (Length:  9:23 min.)

"The Use of Surveys as an Advocacy Tool"
Lydia Lewis
National Depressive and Manic-Depressive Association
USA
RealMedia  Audio  (Length:  16:05 min.)

"The Importance of Self-Support Groups for Bipolar Disorder and Suicide"
Patrick McKeon, M.D.
AWARE
Ireland
RealMedia  Audio  (Length:  17:50 min.)

"Internet Education, Support and Advocacy"
Martha Hellander
The Child and Adolescent Bipolar Foundation
USA
RealMedia  Audio  (Length:  19 min.)

"The Finnish Model of Advocacy"
Hilkka Kärkkäinen
AFFINITY-Finnish Central Association
Finland
RealMedia  Audio  (Length:  16:04 min.)

"Hidden Illness, Hidden Patients, Hidden Costs"
Rodney Elgie
GAMIAN-Europe
United Kingdom
RealMedia  Audio  (Length:  16:43 min.)

"Concluding Remarks"
Lydia Lewis
RealMedia  Audio  (Length:  5:17 min.)


10:15 a.m.

Panel Discussion
RealMedia  Audio  (Length:  28:51 min.)

10:45 a.m.
 
Break
11:00 a.m.

"Rapid Communications Session"
Moderator: David Miklowitz, Ph.D.

"Perceptions and Impact of Bipolar Disorder: How Far Have We Really Come?"
Lisa C. Goodale, M.S.W.
RealMedia  Audio  (Length:  16:20 min.)

"Brain Morphology Differences Correspond to Clinical Subtypes in Affective Disorder"
Nancy Honeycutt, Ph.D.
RealMedia  Audio  (Length:  14:43 min.)

"Cognitive Therapy for Bipolar Affective Disorder - A Randomised Controlled Study"
Dominic Lam, Ph.D.
RealMedia  Audio  (Length:  18:50 min.)

"ICD-10 versus DSM-IV Diagnostic Criteria for Bipolar Mania: A Clinical Comparison"
Rasmus W. Licht, M.D., Ph.D.
RealMedia  Audio  (Length:  11:38 min.)


12:00 Noon
 
Lunch (on your own)

AFTERNOON
 
1:00 p.m.

Interactive Sessions: Ask the Experts

1. "Treating the Complex Patient"
Athansio Koukopoulos, M.D. [audio and slides]
RealMedia  Audio  (Length:  55:07 min.)

2. "Establishing a Specialty Clinic for Children and Adolescents"
David Axelson, M.D., Amy Schlonski, M.S.W., and Susan Wassick, R.N. [audio and slides]
RealMedia  Audio  (Length:  1 hr. 2:37 min.)

3. "A Pilot Study for Early Detection and Prevention of Relapse in S
ão Paulo State, Brazil"
Valentim Gentil, M.D.
[audio and slides]
RealMedia  Audio  (Length:  13:39 min.)

4. "Clinical Epidemiology and Treatment Access"
Giovanni de Girolamo, M.D.
[audio and slides]
RealMedia  Audio  (Length:  23:13 min.)

5. "Caring for Pregnant and Postpartum Women with Bipolar Disorder"
Adele Viguera, M.D.
[audio and slides]
RealMedia  Audio  (Length:  41:29 min.)

6. "How Does Lithium Compare to Other Treatments in the Management of Bipolar Disorder?"
Frederick K. Goodwin, M.D.
[audio file]
RealMedia  Audio  (Length:  59:02 min.)

7. "Legal and Ethical Issues in the Assessment and Treatment of Bipolar Disorder Patients"
Robert M. Wettstein, M.D.
[audio and slides]
RealMedia  Audio  (Length:  32:33 min.)  


2:15 p.m.
 
Break
2:30 p.m.

Psychosocial Treatment Workshops

1. Cognitive Behavioral Therapy for Bipolar Disorder
Michael Otto, Ph.D.
[audio and slides]
Noreen Reilly Harrington, Ph.D.
Adobe .pdf  Audio  (Length:  1 hr. 53:06 min.)
*Click here to download Adobe Acrobat Reader to view slides.

2. Family Therapy of Bipolar Disorder
David Miklowitz, Ph.D. [audio and slides]
RealMedia  Audio  (Length:  2 hr. 3:20 min.)

3. Interpersonal and Social Rhythm Therapy
Ellen Frank, Ph.D. [audio and slides]
RealMedia  Audio  (Length:  1 hr. 58:39 min.)


4:30 p.m.

Adjournment

Introduction | Proceedings | Bipolar Conferences Home

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