Stanley Center for the Innovative Treatment of Bipolar Disorder

THIRD INTERNATIONAL CONFERENCE 
ON BIPOLAR DISORDER



Introduction

Proceedings

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Schedule


DAY 1: THURSDAY, JUNE 17, 1999

MORNING

7:45 a.m. Registration and Continental Breakfast
8:30 a.m. Background
David J. Kupfer, M.D.

Session I: "Treatment of Bipolar Depression: A Review of New Approaches"
Chair: Ellen Frank, Ph.D.
8:45 a.m. "Interpersonal and Social Rhythm Therapy Prevents Depressive Symptomatology in Bipolar I Patients"
Ellen Frank, Ph.D.
RealAudio
MP3 (Length:  31:40 min.)
9:05 a.m. "Multifamily Group Treatment for Bipolar Depression"
Gabor I. Keitner, M.D.
RealAudio
MP3 (Length:  21:16 min.)  
9:25 a.m. "Treatment of Bipolar Depression"
Gary S. Sachs, M.D.
RealAudio MP3 (Length:  22:13 min.)
9:45 a.m. Panel Discussion
RealAudio MP3 (Length:  14:02 min.)
10:00 a.m. Break

Session II: "Epidemiology/Comorbidity"
Chair: Kathleen R. Merikangas, Ph.D.
10:15 a.m. "Epidemiology of Bipolar Spectrum Disorder in Community Based Studies"
Jules Angst, M.D.
RealAudio
MP3 (Length:  17:06 min.)  
10:35 a.m. "Comorbidity of Migraine and Affective Disorders"
Kathleen R. Merikangas, Ph.D.
RealAudio MP3 (Length:  23:18 min.)
10:55 a.m. "Bipolar Disorder during Adolescence and Young Adulthood in a Community Sample"
Peter M. Lewinsohn, Ph.D.
RealAudio
MP3 (Length:  18:14 min.)
11:15 a.m. "Personality Disorder or Bipolar Illness: New Thoughts"
Robert M.A. Hirschfeld, M.D.
RealAudio
MP3 (Length:  19:14 min.)
11:45 a.m. Panel Discussion
RealAudio MP3 (Length:  14:19 min.)
12:00 Noon Lunch (on your own)

AFTERNOON

Session III: "Neuroscience and Neuroimaging"
Chairs: Husseini K. Manji, M.D., F.R.C.P. and Perry F. Renshaw, M.D., Ph.D.
1:00 p.m. "Recent Status of Genetic Studies in Bipolar Disorder"
Steven M. Paul, M.D.
RealAudio MP3 (Length:  32:40 min.)
1:30 p.m. "Signaling Pathways and Gene Expression:  Molecular Mechanisms Underlying Mood Stabilization in the Brain"
Husseini K. Manji, M.D., F.R.C.P.
Note:  RealAudio only
RealAudio
(Length:  24:12 min.)
2:00 p.m. "Regulation of Gene Expression in the CNS:
*FosB: A Molecular Mediator of Long-term Neural Plasticity"

Eric J. Nestler, M.D., Ph.D.

RealAudio MP3 (Length:  26:14 min.)
2:30 p.m. Break
2:45 p.m. "Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging"
Perry F. Renshaw, M.D., Ph.D.
RealAudio MP3 (Length:  32:22 min.)
3:15 p.m. "Current Status of MR Studies in Bipolar Disorder"
Gregory J. Moore, Ph.D.
RealAudio
MP3 (Length:  23:57 min.)
 
3:45 p.m. "fMRI Studies of Affect Recognition in Healthy Adolescents and Adults with Bipolar Disorder"
Deborah Yurgelun-Todd, Ph.D.
RealAudio
MP3 (Length:  33:49 min.)
 
4:15 p.m. Panel Discussion
4:45 p.m. Adjournment
5:00 p.m. Poster Session
7:00 p.m.-
9:00 p.m.
Reception - The Grand Concourse Restaurant

DAY 2: FRIDAY, JUNE 18, 1999

MORNING

 
7:45 a.m. Registration and Continental Breakfast
8:30 a.m. Background
Ellen Frank, Ph.D.

Session IV: "Impact of Select Conditions on the Treatment of Bipolar Disorder"
Chair: Michael E. Thase, M.D.
8:45 a.m. "The Use of Medications in Bipolar Women during Pregnancy and Postpartum"
Lori Altshuler, M.D.
RealAudio
MP3 (Length:  26:27 min.)  
9:15 a.m. "Complex Bipolarity: Temperament, Anxious Comorbidity and Mixed States"
Hagop S. Akiskal, M.D.

Note:  Lecture divided into 2 files
RealAudio MP3 (Length:  31:39 min.) 
RealAudio MP3 (Length:  2:01 min.)
9:45 a.m. Break
10:00 a.m. "Impact of Substance Abuse on the Course and Treatment of Bipolar Disorder"
Michael E. Thase, M.D.
Note:  Lecture divided into 2 files
RealAudio MP3 (Length:  31:30 min.) 
RealAudio MP3 (Length:  7:25 min.)
10:30 a.m. Panel Discussion
Note:  Lecture divided into 3 files
RealAudio MP3 & MP3 (Length:  5:02 min.)  
RealAudio MP3 (Length:  6:11 min.)  
RealAudio MP3 (Length:  11:21 min.)  
11:00 a.m. Meeting to Establish International Society for Bipolar Disorders
RealAudio MP3 (Length:  19:00 min.)  
11:45 a.m. Lunch (on your own)

AFTERNOON

 
1:00 p.m. Interactive Sessions: Ask the Experts
1. "Comorbidity and Its Clinical Relevance for Bipolar Spectrum Disorders"
Giovanni B. Cassano, M.D.
RealAudio
MP3 (Length:  56:26 min.)  
2. "Diagnostic and Biological Aspects of Treatment Specificity in Bipolar Disorders"
Alan G. Mallinger, M.D. and Jair C. Soares, M.D.
Note:  No audio file available
3. "Agitated Depression"
Athanasio Koukopoulos, M.D.

RealAudio MP3 (Length:  51:16 min.)
4. "Differentiating among Multiple Treatment Opportunities for Bipolar Depression"
William Z. Potter, M.D., Ph.D.
RealAudio MP3 (Length:  51:13 min.)
2:00 p.m. Break

Session V: "New Pharmacotherapies"
Chair: Fouzia Laghrissi-Thode, M.D.
2:15 p.m. "Methodological Issues and Practical Difficulties in Conducting Clinical Trials in Bipolar Disorder"
John A. Ascher, M.D.

RealAudio MP3 (Length:  28:29 min.)
2:45 p.m. "Combination Treatment in Bipolar Disorder"
Atul Pande, M.D., F.R.C.P.C.
RealAudio MP3 (Length:  30:44 min.)
3:15 p.m. Break
3:30 p.m. "Novel Endpoints for Clinical Trials in Bipolar Disorder"
Fouzia Laghrissi-Thode, M.D.
RealAudio MP3 (Length:  27:59 min.)
4:00 p.m. "Use of Antipsychotics in Bipolar Disorder"
Mauricio Tohen, M.D., Dr.P.H.
Note:  While the content of this file is understandable, there are defects in the original recording.
RealAudio MP3 (Length:  23:15 min.)
4:30 p.m. Panel Discussion
RealAudio MP3 (Length:  23:32 min.)  
5:00 p.m. Adjournment
5:00 p.m.   Poster Session
7:00 p.m. Cocktails - The Carnegie Museums of Pittsburgh
8:00 p.m. Dinner - The Carnegie Museums of Pittsburgh
"Present and Future Role of Advocacy Associations in the Management of the Mentally Ill: Needs, Myths, Realities and Hopes at the Edge of the Third Millennium"

Speaker: Paolo Lucio Morselli, M.D.
Vice President, IDEA
Secretary General, GAMION


DAY 3: SATURDAY, JUNE 19, 1999


MORNING

 
7:45 a.m. Registration and Continental Breakfast
8:30 a.m.  Background
Michael E. Thase, M.D.

Session VI: "Suicide"
Chair: Kay Jamison, Ph.D.
8:45 a.m. "Genetics of Suicide"
Sylvia G. Simpson, M.D.
RealAudio MP3 (Length:  19:12 min.)
9:05 a.m. "Neuropathology of Suicide"
Susan E. Bachus, Ph.D.
RealAudio
MP3 (Length:  17:20 min.)  
9:25 a.m. "Reduced Risk of Suicidal Behavior in Bipolar Disorder Patients during Long-term Treatment with Lithium"
Ross J. Baldessarini, M.D.
Note:  MP3 only
MP3
(Length:  22:50 min.)
9:45 a.m. Panel Discussion
RealAudio MP3 (Length:  15:02 min.)  
10:00 a.m. Break

Session VII: "Access, Services, and Health Policy Issues"
Chair: Kelly J. Kelleher, M.D., M.P.H.
10:15 a.m. "Principles of Population-Based Care of Patients with Bipolar Disorder"
Michael Von Korff, Sc.D.
RealAudio MP3 (Length:  18:22 min.)
10:35 a.m. "Clinician Incentives for Improving Quality"
Howard Goldman, M.D., Ph.D.
RealAudio MP3 (Length:  20:02 min.)
10:55 a.m. "VA Cooperative Study #430:  Reducing the Efficacy-Effectiveness Gap in Bipolar Disorder"
Mark Bauer, M.D.
Note: MP3 only
MP3
(Length:  23:02 min.)
11:15 a.m. Panel Discussion
RealAudio MP3 (Length:  14:29 min.)
11:30 a.m. Lunch (on your own)

Day 3: Saturday, June 19, 1999


AFTERNOON

 
1:00 p.m. Interactive Sessions: Ask the Experts

A. "Risk Factors"
Paula J. Clayton, M.D.
Note:  Lecture divided into 3 files

RealAudio MP3 (Length:  41:43 min.)
RealAudio MP3 (Length:  20:46 min.)
RealAudio MP3 (Length:  10:32 min.)

B. "Bipolar Disorder and Suicide"
Jan A. Fawcett, M.D.
No audio file available

C. "Family Issues"
David Miklowitz, Ph.D.
Note:  RealAudio incomplete, MP3 divided into 2 files
RealAudio
MP3 & MP3 (Length:  61:46 min.)

D. "Medication Guidelines and Patient Education for Patients with Bipolar Disorder"
Trisha Suppes, M.D., Ph.D.
Note:  Lecture divided into 3 files
RealAudio MP3 (Length:  48:58 min.)
RealAudio MP3 (Length:  4:15 min.)
RealAudio MP3 (Length:  10:15 min.)

E. "Clinical-Legal Issues: Work Disability, Criminal Responsibility, and Civil Responsibility"
Robert M. Wettstein, M.D.
Note:  Lecture divided into 3 files
RealAudio MP3 (Length:  37:25 min.)
RealAudio MP3 (Length:  24:57 min.)
RealAudio MP3 (Length:  13:13 min.)

2:15 p.m. Break
2:30 p.m. Family Psychoeducational Workshop

Family/Consumer Track

Steve S. Carter, Ph.D.
Daniel P. Cole, M.D.
Holly Swartz, M.D.
Steven J. Verfaille, L.S.W.
Lee K. Wolfson, M.Ed.

RealAudio MP3 (Length:  57:04 min.)

Provider Track

Debra Frankel, L.S.W.
Alan G. Mallinger, M.D.
Noreen Reilly-Harrington, Ph.D.

Note:  Lecture divided into 3 files
RealAudio MP3 (Length:  49:35 min.)
RealAudio MP3 (Length:  12:40 min.)
RealAudio MP3 (Length:  29:57 min.)

4:30 p.m. Adjournment

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