Research into the causes of Schizophrenia, Bipolar Disorder, and Related Illnesses

Schizophrenia Liability Genes Among African Americans

Funding for this work provided by the NIMH
ref. #R29 MH53459

Purpose:

The goal of this study is to identify genes underlying liability to schizophrenia. This research will be conducted in the African American population, who have been underserved in mental health research. This study will investigate schizophrenia in both nuclear families and multigenerational multiplex families (families with more than one affected person). We hope that identification of predisposing genes for schizophrenia will facilitate research into pathophysiological mechanisms which may in the future lead to new treatments for the illness.

Eligibility:

African American families with individuals affected with schizophrenia or schizoaffective disorder.
Unaffected parents, siblings and in some cases extended family members (e.g., uncles, cousins) are also needed to participate.
Affected participants must be 14+ years old, unaffected must be 18+ years.

Procedures:

All participants will be asked to undergo the following procedures:

Blood Draw
Diagnostic Interview
Family Interview
Computerized neurocognitive tests

All procedures will be carried out by a qualified and experienced clinical interviewer. All procedures can be done in the participant’s home or other convenient location. In most cases, all procedures can be completed in one session.

Payments:

All participants will be paid $100 upon completion of the study in appreciation for their time and contribution.

This is not a treatment study. Thus, there will be no changes in treatment requested to participate in this study. All information will be kept strictly confidential.

For more information, please call 1-877-363-5895.