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INVESTIGATION
Patrick Sullivan, M.D., FRANZCP, University of North Carolina, Chapel Hill, NC
Patrick Sullivan,
M.D., FRANZCP,
is a Professor of Genetics,
Psychiatry, and Epidemiology at UNC and Foreign Adjunct Professor, Karolinska
Institutet, in Stockholm, Sweden.
Dr. Sullivan received his BS from the University of Notre
Dame in 1981, his MD degree from the
University
of
California
,
San Francisco
in 1988, and completed his psychiatry residency at the
University
of
Pittsburgh
. He received his FRANZCP in
Christchurch
,
New Zealand
in 1994. The over-arching theme of Dr. Sullivan’s research is the attempt to
understand the etiology of a number of important complex disorders that
represent public health problems. These disparate disorders have several
common features. They are common, etiologically heterogeneous, and exhibit
complex patterns of inheritance. Their study is made more difficult by the
inaccessibility of the brain regions of interest and the absence of compelling
animal models. Dr. Sullivan believes that in order to develop an
understanding of these disorders the integration of findings from multiple
investigative approaches such as bioinformatics, epidemiology, linkage
analysis, and association studies are of utmost importance. His lab applies
these methods to several research areas such as schizophrenia, smoking
behavior, chronic fatigue syndrome, pharmacogenetics, autism, and eating
disorders. He has active research collaborations throughout the
United States
,
Holland,
Sweden, Australia, Norway, and
Brazil. Dr. Sullivan has published 153 journal articles, 17 chapters or invited
articles, and 2 miscellaneous items. He has recently developed TAMAL
(Technology And Money Are Limiting) web site (in collaboration with Bradley
Hemminger and Billy Saemlim) to help identify promising single nucleotide
polymorphisms (SNPs) for further genetic investigation. TAMAL is a platform
independent web-based application available free of charge at http://neoref.ils.unc.edu/tamal.
Dr. Sullivan’s lab has also developed SLEP (Sullivan Lab Evidence Project)
website (https://slep.unc.edu/evidence/)
which allows users to search the accumulated data to find the evidence
in support of the involvement of a particular genomic region with a set of the
disorders of central importance in psychiatry – autism, bipolar disorder,
major depressive disorder and schizophrenia. Recently, Dr. Sullivan joined The
Genetic Association Information Network (GAIN) Collaborative Research Group
and will be involved in the investigation of the genetic basis of common
diseases through a series of genome wide association studies. For more
information on Dr. Sullivan’s work, please visit: http://www.med.unc.edu/~pfsulliv/.
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