The Clinical and Translational Affective Neuroscience
Program is a large group of dedicated clinical neuroscientists in the Department of Psychiatry,
Western Psychiatric Institute and Clinic, University of Pittsburgh School of
Medicine, and directed by Dr. Mary Phillips. The group uses multimodal
imaging techniques to examine the function and structural integrity of
neural circuits supporting human emotion processing and emotion regulation. Our
long-term research goal is use these neuroimaging techniques to identify
specific functional and structural abnormalities in neural systems underlying
the different processes important for emotion processing and emotion regulation
that may be present as objective biomarkers of disorder in individuals
with major psychiatric illnesses, including bipolar disorder, unipolar
depression, schizophrenia, and obsessive-compulsive disorder.
The identification of these objective biomarkers of psychiatric disorders is a
crucially important step toward improving the accuracy and speed of diagnosis in
many individuals who suffer from these major psychiatric illnesses. Objective
biomarkers can also be used to identify as early as possible those individuals
at genetic risk of developing a major psychiatric illness who are most likely to
develop the illness in the future. These biomarkers can also inform the choice
of treatment for individuals suffering from these illnesses.
Who are we?
Mary L. Phillips, MD
Learn more about Mary L. Phillips's Research
Affiliated Research Fellows