Belle SH, Seaberg EC, Ganguli M, Ratcliff G, DeKosky ST, Kuller LH: The effect of education adjustment on the sensitivity and specificity of a cognitive screening battery for dementia: results from the MoVIES project. Neuroepidemiology, 15: 321-329, 1996.
The Monongahela Valley Independent Elders Survey (MoVIES) used a
multiphase process to identify demented persons among 1,366 randomly
selected noninstitutionalized individuals 65 years and older. Raw test
scores from a cognitive screening battery were used to identify
cognitively impaired individuals who were referred for a clinical
evaluation. Subsequently, test scores were adjusted for education and
gender within age strata. Adjusting test scores affected sensitivity
for dementia only among the most educated, increasing sensitivity
among younger subjects and decreasing among the older subjects.
Specificity increased among the least educated and the oldest
subjects. Overall, the adjusted criteria did not perform as well as
the unadjusted criteria in this sample. Adjustment for education will
not necessarily improve the ability of a screening battery for
cognitive function to identify demented persons, particularly if
unadjusted scores perform well.