ASSOCIATED CURRENT STUDIES
Response to Emotion in ASD Children &
Teens (REACT) Study-This study is
completed.
Dr. Carla
Mazefsky, PhD, University of Pittsburgh
Mentored Patient-Oriented Research Career Development Award (K23),
National Institutes of Health
Poor emotional
control is a problem for many children with autism spectrum disorders
(ASD), but the behavioral and neural underpinnings of this problem
are not well understood. This research study will explore the
neurobiological basis of emotional experiences in autism. The
objectives are to better understand how emotional processes differ in
individuals with and without ASD, including differences in brain
functioning and how factors like pubertal status and associated anxiety
and mood symptoms play a role. This study includes individuals
between the ages of 12 and 19 years old who have an ASD and those who do
not have any developmental or mental health problems.
Eligible participants
and their parents will complete a series of questionnaires about the
participant's emotional and behavioral functioning. Participants
will also complete three tasks in a functional magnetic resonance
imaging (fMRI) scanner. fMRI is a painless way of taking pictures
of the brain while a person is completing an activity. Also while
in the scanner, eye tracking will be completed, which is a noninvasive
means of tracking where the participants' eyes are looking.
Information from this study will help to identify specific differences
in emotional functioning in autism, which will enable the development of
more targeted and effective treatments.

Please click on image to see an electronic
version of REACT study brochure |