SEEKING WOMEN RECOVERED FROM ANOREXIA OR BULIMIA NERVOSA

The Anorexia and Bulimia Nervosa Research team at the University of Pittsburgh Medical Center is currently conducting a study to understand the biological aspects of eating disorders. We are using a brain imaging technology called Positron Emission Tomography (PET). PET is a method used to take pictures of the body, in this case, the brain. Specifically, we are looking at a chemical in the brain called serotonin. Serotonin seems to play an important role in regulating anxiety, mood and other symptoms found in anorexia. Some of our previous studies suggest that people who have had anorexia may have altered activities of serotonin receptors and serotonin transporters. In this research study, we want to examine how serotonin responds to an 8-week treatment of Fluoxetine (the generic name for Prozac). We will compare brain scans of women who have recovered from anorexia with women who have never had an eating disorder. The study may provide important information about changes in brain chemistry associated with eating disorders.  

This study is funded by the National Institute of Mental Health.

Who may be eligible?

• Women ages 18-45 who have recovered from Anorexia or Bulimia
• Currently medication-free (birth control pills acceptable)
• Not pregnant or nursing

What does the study involve?

• Brain imaging (PET or fMRI)
• A blood sample and physical exam
• Phone interviews, neurocognitive assessments, and self-report questionnaires
• 2 visits to Pittsburgh (at an 8 week interval)
• 8 weeks of Fluoxetine treatment
  
  Note: All expenses incurred during the study (e.g. travel expenses and physical exam) are paid for by the study.  In addition, participants will be compensated up to $1300 upon completion of the study.

If you are interested in participating or obtaining more information, contact us via the following:

• Submit a Contact Form online
• Call toll-free at: 1-866-265-9289
• e-mail: EDResearch@upmc.edu
• e-mail: Kathy Plotnicov - PlotnicovKH@upmc.edu or Sharon Barnes - barnessd@upmc.edu

Contact info: 1-866-265-9289   EDResearch@upmc.edu
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The information contained in this site is for informational purposes only and is not intended to offer medical advice for the treatment of eating disorders, or to be a substitute for professional medical or psychological advice, diagnosis, or treatment.