FASTS
Fatty
Acid Supplementation Trials in Schizophrenia
Omega-3 Fatty Acids
Omega-3 fatty acids, which are found in fish and fish oils,
are essential for normal functioning of the body. Specifically, they are
important components in the cell membranes throughout the body, in particular,
those of the eye and brain.
Past Research
In the past several
years, scientists have found that there are decreases in omega-3 fatty acids in
certain cells in patients with schizophrenia and schizoaffective disorders. It
is believed that reduction in membrane omega-3 fatty acids can disrupt the
proper functioning of cells, including brain cells. These research
findings led to the idea of using omega-3 fatty acids to supplement the
antipsychotic drugs in order to improve the clinical situation. A few studies
have been conducted testing whether omega-3 fatty acids can be helpful to reduce
symptoms. Most, but not all, the studies show that omega-3 fatty acids can be
helpful in reducing some of the symptoms associated with schizophrenia.
It may interest you to know omega-3 fatty acids are also helpful in other
medical conditions, particularly in reducing the risk of heart disease.
In
this research study, called Fatty Acid Supplementation Trial in Schizophrenia,
we want to understand if 6 months of omega-3 fatty acids supplementation improve
the signs and symptoms of schizophrenia. This research may lead to better
treatments for schizophrenia.
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This is
a supplementation trial; you will not have to change any of your current
medication.
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Participants will be seen regularly by a physician during the study.
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All
clinical assessments, brain scans and research medication will be provided
at no cost.
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Participants will be reimbursed for travel costs.
For details about the study or
any other information, please contact one of us:
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