ASSOCIATED CURRENT STUDIES

Neurocognitive Basis of Language Processing in Autism

Dr. Diane Williams, PhD, Duquesne University
Mentored Patient-Oriented Research Career Award (K23)

This research study will explore the neurobiologic basis of language processing in autism.  The objectives are to clarify the neurobiologic and neurodevelopmental mechanisms underlying language processing problems in developmental disabilities, particularly autism; to characterize the functional and anatomical brain systems underlying processing of complex linguistic concepts in high-functioning individuals with autism; and to illustrate the functional and anatomical brain systems underlying processing in this population.

The first research studies will examine the comprehension of ironic and metaphoric language and theory of mind in 30 older adolescents and adults with high-functioning autism. The data from the behavioral studies will be integrated with data from fMRI studies conducted under the direction of Dr. Just.  The hope is that clearer understanding of the underlying neural mechanisms will guide the development of more efficient and effective therapeutic intervention, affecting positive change in the linguistic processing and adaptive functioning of individuals with autism. 

 
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© 2006 CeFAR at the University of Pittsburgh • Site last updated November, 2008