COMPLEX COMBINATION THERAPY FOR REFRACTORY BIPOLAR PATIENTS

10/10/97


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Table of Contents

COMPLEX COMBINATION THERAPY FOR REFRACTORY BIPOLAR PATIENTS

T3 and T4 Augmentation in Refractory Depression: Percent Response; (Frye et al., 1996)

CGI Prophylaxis Response vs. Previous Phase

Carbamazepine (CBZ) and Oxcarbazepine (OXCBZ) in Acute Mania 19 Double-Blind Studies

Controlled and Partially-Controlled Studies of Carbamazepine (CBZ) and Oxcarbazepine Prophylaxis in Affective Illness

Carbamazepine Prophylaxis: Equal Rates Against Manic vs. Depressive Episodes

Adjunct Medications Used at NIMH Discharge

Rationales for Combination Therapy

Principles in the Treatment of Bipolar Illness

Controlled Studies of Valproate in Acute Mania

Relative Efficacy of Valproate in Prophylaxis of Mania Versus Depression

L-Type Calcium Channel Blockers in Affective Illness

Algorithm for “Augmentation/Switching Strategies,” Treatment of Bipolar Disorder, Manic Phase/Dysphoric Type

PPT Slide

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PPT Slide

Carbamazapine Properties Relevant to Pharmacokinetics and Drug Interactions

PPT Slide

PPT Slide

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PPT Slide

PPT Slide

PPT Slide

PPT Slide

Steps in the Treatment Algorithm of the Bipolar Patient

Steps in the Treatment Algorithm of the Bipolar Patient (Cont’d)

Steps in the Treatment Algorithm of the Bipolar Patient (Cont’d)

Steps in the Treatment Algorithm of the Bipolar Patient (Cont’d)

Steps in the Treatment Algorithm of the Bipolar Patient (Cont’d)

Carbamazepine Drug Interactions

Carbamazepine Drug Interactions

Speculative Differential Approaches to Bipolar Subtypes

Neuroleptic Use in Cania

Neuroleptic Use in Mania

Drugs in the Prevention of Manic Depressive Episodes & Cycling (Strengths of Supporting Evidence + to ++++)

Drugs in the Prevention of Manic Depressive Episodes & Cycling (Cont’d)

Drugs in the Prevention of Manic Depressive Episodes & Cycling (Cont’d)

Drugs in the Prevention of Manic Depressive Episodes & Cycling (Cont’d)

Comparative Effects of Two Anticonvulsant Mood Stabilizers in Bipolar Illness

Comparative Clinical and Side-Effects Profiles of Lithium, Nimodipine, and the Putative Mood-Stabilizing Anticonvulsants (Preliminary Clinical Impressions)

Comparative Clinical and Side-Effects Profiles of Lithium, Nimodipine, and the Putative Mood-Stabilizing Anticonvulsants (Cont’d) (Preliminary Clinical Impressions)

Author: WPIC

Home Page: http://www.wpic.pitt.edu/stanley/2ndbipconf/