Percentage of Manic Patients with 20% or Greater Improvement

At Day 5

At Endpoint

n = 34

SADS = Schedule for Affective Disorder and Schizophrenia

ADRS = Affective Disorders Rating Schedule

-Bowden, ACNP 1996

0

10

20

30

40

50

60

ADRS Elation

ADRS Mania

SADS Elevated Mood

SADS Less Need for Sleep

SADS Motor Hyperactivity

SADS Increased Activity

Behavior & Ideation Subscale

Manic Syndrome Subscale

> 0.8 mmol/L

< 0.8 mmol/L

0

10

20

30

40

50

60

70

ADRS Psychosis

ADRS Elation

ADRS Mania

SADS Less Need for Sleep

SADS Motor Hyperactivity

SADS Increased Activity

Behavior & Ideation

Subscale

Manic Syndrome Subscale

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