Epidemiology 2400:  Class Assignments

   

 

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Session 1:         1/5/04              Measures and Concepts

 

Kaplan, R.M., Sallis, J.F., & Patterson, T.L.  (1993).  Health and human behavior. New York:  McGraw-Hill.  Chapter 2

 

Kerlinger, F.N. (1973).  Foundations of behavioral research (2nd ed.).  New York:  Holt, Rinehart, & Winston.  Chapters 3, 26-27.

 

Lecture:  History of epidemiology; epidemiology methods and measurement of behavior;

 importance of behavior in disease.

 

 

.Session 2:        1/12/04            SES Differences in Health

 

Adler, N.E., Boyce, T., Chesney, M.A., Cohen, S., Folkman, S., Kahn, R. L., & Syme, S.L.  (1994).  Socioeconomic status and health:  The challenge of the gradient.  American Psychologist, 49, 15-24.

 

Diez Roux, A.V., Merkin, S.S., Arnett, D., et al. (2001) Neighborhood of residence and incidence of coronary

 heart disease.  New England Journal of Medicine, 345, 99-106.

 

Kaplan, G.A., Pamuk, E.R., Lynch, J.W., et al.  (1996).  Inequality in income and mortality in the United States: Analysis of mortality and potential pathways.  British Medical Journal, 312, 999-1003.

 

Poulton, R., Caspi, A., Milne B.J., Thomson, W.M., Taylor, A., Sears, M.R., & . Moffitt, T.E. (2002).  Association between children’s experience of socioeconomic disadvantage and adult health: A life-course study.  Lancet, 360, 1640-45. 

 

Lecture: Role of SES in health.

    

Assignment: Develop a self-report measure of a behavioral construct; plan how you will assure that it is a reliable and valid measure. 

 

 

HOLIDAY:      1/19/04            Martin Luther King, Jr. Day

                                               No class. University closed

 

 

Session 3:         1/26/04           Sex and Ethnic Differences in Health

 

          Williams, D.R., & Collins, C.C.  (1995).  U.S. socioeconomic and racial differences in health patterns and

            explanations.  Annual Review of Sociology, 21, 349-386.

 

            Krieger, N., & Sidney, S.  (1996).  Racial discrimination and blood pressure: The CARDIA study of young black

            and white adults.  American Journal of Public Health, 86, 1370-1378.

 

           Schneider, E.C., Zaslavsky, A.M., & Epstein, A.M.  (2002).  Racial disparities in the quality of

           care for enrollees in medicare managed care.  Journal of the American Medical Association, 287,

           1288-1294.

 

            Schulman, K.A.,  Berlin, J.A., Harless, W., Kerner, J.F., Sistrunk, S., Gersh, B.J., Dube, R.,

            Taleghani, C.K., Burke, J.E., Williams, S., Eisenberg, J.M., & Escarce, J.J. (1997).  Effect of

            race and sex on physicians’ recommendations for cardiac catherization.  New England Journal of

            Medicine, 337, 1209-14.

 

Steffan, P.R., McNeilly, M., Anderson, N., & Sherwood, A. (2003).  Effects of perceived

 racism and anger inhibition on ambulatory blood pressure in African Americans.  Psychosomatic

 Medicine 65, 746-750. 

 

           Lecture: Sex and ethnic differences in health

 

           Assignment: What do the Krieger and Steffan articles tell us about the impact of racism?

 

 

Session 4:         2/2/04             Psychosocial Stress

 

            Baum, A., Cohen, L., & Hall, M.  (1993).  Control and intrusive memories as possible

            determinants of chronic stress.  Psychosomatic Medicine, 55, 274-286.

 

            Matthews, K.A. & Gump, B. (2002). Chronic work stress and marital dissolution increase risk

            of post-trial mortality in men from the Multiple Risk Factor Intervention Trial.  Archives of Internal

            Medicine, 1162, 309-315.

 

             McEwen, B.S.  (1998) Protective and health-damaging effects of stress mediators.  New

             England Journal of Medicine, 338, 171-179.

 

             Schulz, R., & Beach, S.F. (1999) Caregiving as a risk factor for mortality: the Caregiver Health 

             Effects Study.  Journal of the American Medical Association, 282, 2215-2219. 

 

           Lecture:  Stress

 

          Assignment: Design a measure of stress; indicate how you are going to test its reliability

          and validity.

 

 

Session 5:         2/9/04               Coping and Social Support

 

            Everson, S. A., Goldberg D. E., Kaplan G. A., Julkunen J., & Salonen J. T. (1998) Anger

           expression and incident hypertension.  Psychosomatic Medicine, 60, 730-735.

 

           House, J.S., Robbins, C., & Metzner, H.L.  (1982).  The association of social relationships and

           activities with mortality:  Prospective evidence from the Tecumseh Community Health Study. 

           American Journal of Epidemiology, 116, 123-140.

 

           Kaplan, G.A., Salonen, J.T., Cohen, R.D., Brand, R.J., Syme, S.L., & Puska, P.  (1988).  Social

           connections and mortality from all causes and from cardiovascular disease: Prospective evidence

           from eastern Finland.  American Journal of Epidemiology, 128, 370-380.

 

           Powell, L.H., Shahabi, L., & Thoresen, C.E.  (2003).  Religion and spirituality: Linkages to

           physical health.  American Psychologist, 58, 36-52.

 

           Smyth, J., Steon, A., Hurewitz, A. & Kaell, A.  (1999).  Effects of writing about stressful

           experiences on symptom reduction in patients with asthma or rheumatoid arthritis: A randomized

           trial.  Journal of the American Medical Association, 281, 1304-1309. 

 

Vogt, T.M., Mulloly, J.P., Ernst, D., Pope, C.R., & Hollis, J.F.  (1992).  Social  

networks as predictors of ischemic heart disease, cancer, stroke and hypertension:  Incidence,

survival and mortality.  Journal of Clinical Epidemiology, 45, 659-666.

 

 Lecture: Coping and Social Support

 

           Assignment: Why or why not are social relationships protective and in whom?

 

 

Session 6:         2/16/04            Personality

 

            Christensen, A.J., Ehlers, S.L., Wiebe, J.S., Moran, P.J., Raichle, K., Ferneyhough,  K., Lawton,

             W.J.  (2002).  Patient personality and mortality: A 4-year prospective examination of chronic

             renal insufficiency.  Health Psychology, 21, 315-320. 

 

            Everson, S.A., Goldberg, M.S., Kaplan, G.A., et al.  (1996).  Hopelessness and risk of mortality

            and incidence of myocardial infarction and cancer.  Psychosomatic Medicine, 58, 113-121.

 

            Martin, L.R., Friedman, H.S., Tucker, J.S., Schwartz, J.E., Criqui, M.H., Wingard, D.L., &

            Tomlinson-Keasey, C.  (1995).  An archival prospective study of mental health and longevity. 

            Health Psychology, 14, 381-387.

 

            Schulz, R., Bookwala, J., Knapp, J.E., Scheier, M., & Williamson, G.M.  (1996).  Pessimism,

            age, and cancer mortality.  Psychology and Aging, 11, 304-309.

 

             Lecture: Personality and Health: Optimism

 

 Assignment: Prepare to present each paper; no written assignment

 

 

Session 7:         2/23/04            Depression

 

           Frasure-Smith, N. & Lesperance F.  (2003). Depression—A cardiac risk factor in search of a

           treatment.  Journal of the American Medical Association, 289, 3171-3173. 

 

           Frasure-Smith, N., Lesperance, F., Prince, R. H., Verrier, P., Garbert, R. A., Juneau, M.,

           Wolfson, C., & Bourassa, M.G.  (1997).  Randomized trial of home-based psychosocial nursing

           intervention for patients recovering from myocardial infarction.  Lancet, 350, 473-479.

 

           Lin, E.H.B., Katon, W., Von Korff, M., Tang, L., Williams, Jr., J.W., Kroenke, K., Hunkeler, E.,

            Harpole, L., Hegel, M., Arean, P., Hoffing,M., Della Penna, R., Langston, C., Unutzer, J. for the

            IMPACT Investigators . (2003). Effect of improving depression care on pain and functional

            outcomes among older adults with arthritis: A randomized controlled trial. Journal of the American

            Medical Association, 290, 2428-2434.

 

           Roose, S.P., Glassman, A.H., & Seidman, S.N.  (2001).  Relationship between depression and

           other medical illnesses.  Journal of the American Medical Association, 286, 1687-1690.

 

           Writing Committee for ENRICHD Investigators. (2003).  Effects of treating depression and low

           perceived social support on clinical events after myocardial infarction: The Enhancing Recovery in
           Coronary Heart Disease Patients (ENRICHD) Randomized Trial. 
Journal of the American

            Medical Association, 289, 3106-3116. 

 

           Lecture: Depression

 

          Assignment:  Is depression a risk factor for heart disease? 

                                   

 

Session 8:         3/01/04            Obesity and Physical Activity 

Guest Lecturer:    John Jakicic, Ph.D.

 

          Blair, S.N., Kampert, J.B., Kohl, 3rd, H.W., Barlow, C.E., Macera, C.A., Paffenbarger, Jr., R.S.,

          & Gibbons, L.W.  (1996).  Influences of cardiorespiratory fitness and other precursors on

          cardiovascular disease and all-cause mortality in men and women.  Journal of the American

          Medical Association, 276, 205-210.

 

          Makdad, A.H., Ford, E.S., Bowman, B.A., Dietz, W.H., Vinicor, F., Bales, V.S., & Marks, J.S.

          (2003).  Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001, Journal of

          the American Medical Association, 289, 76-79.

 

          Ogden, C.L., Flegal, K.M., Carroll, M.D., & Johnson, C.L. (2002).  Prevalence and trends in

          overweight among US children and adolescents, 1999-2000.  Journal of the American Medical

          Association, 288, 1728-1732.

 

          Paffenbarger, Jr., R.S., Hyde, R.T., Wing, A.L. Lee, I-M., Jung, D.L., & Kampert, J.B.  (1993). 

          The association of changes in physical-activity level and other lifestyle characteristics with mortality

          among men.  New England Journal of Medicine, 328, 538-545.

 

          Whitaker, R.C., Wright, J.A., Pepe, M.S., Seidel, K.D., & Dietz, W.H.  (1997). Predicting

          obesity in  young adulthood from childhood and parental obesity.    New England Journal  of

          Medicine, 337, 869-873.

 

          Assignment:  What behavioral/environmental factors might explain the recent increase in

         obesity in the United States?

 

 

SPRING BREAK:  3/8/04  No class.

 

 

Session 9:  3/15/04  Quality of Life and Violence

 

           Dube, S.R., Anda, R.F., Felitti, V.J., Chapman, D.P., Williamson, D.R., & Giles, W.H.  (2001).

           Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span:

           Findings from the Adverse Childhood Experiences Study.  Journal of the American Medical

           Association, 286, 3089-3096.

 

          Kaplan, R.M. (1990).  Behavior as the central outcome in health care. American

Psychologist, 45, 1211-1220.

 

            Sampson, R.J., Raudenbush, S.W., & Earls, F.  (1997).  Neighborhoods and violent crime: A

            multilevel study of collective efficacy.  Science, 277, 918-924.

 

Schuster, M.A., Stein, B.D., Jacoyx, L.H., Collins, R.L., Marshall, G.N., Elliott, M.NM., Zhou,

 A.J., Kanouse, D.E., Morrison, J.L., & Bery, S.H.  (2001). A national survey of stress reactions

 after the September 11, 2001, terrorist attacks.  New England Journal of Medicine 345, 1507-

1512. 

 

           Singer, M.I., Anglin, T.M., Song, L.Y., & Lunghofer, L.  (1995). Adolescents' exposure to violence and

           associated symptoms of psychological trauma.  Journal of the American Medical  Association, 273, 477-482.

 

            Stein, B.D., Jaycox, L.H., Kataoka, S.H., Wong, M., Tu, W., Elliot, M.N., Fink, A. (2003).  A

             mental health intervention for school children exposed to violence: A randomized controlled

             trial.  Journal of the American Medical Association, 290, 603-611.

 

           Assignment: Is behavior the only appropriate health outcome?

 

  

Session 10:       3/22/04    Infectious Disease and Immune Function

Guest Lecturer: Sheldon Cohen, Ph.D.

 

          Cohen, S., & Herbert, T.B.  (1996).  Health psychology: Psychological factors and physical

            disease from the perspective of human psychoneuroimmunology.  Annual Review of Psychology,

             47, 113-142.

 

            Cohen, F., Kemeny, M.D. Zegans L., Neuhaus, J., & Conant, M.A. (1999). Persistent stress as a predictor of

            genital herpes recurrence.  Archives of Internal Medicine, 159, 2530-2436.

 

            Cohen, S., Tyrrell, D.A., & Smith, A.P.  (1991).  Psychological stress and susceptibility to the

            common cold.  New England Journal of Medicine, 325, 606-612.

 

           Assignment:  Based on the above readings and your own thoughts, what reasons would lead

           you to think that stress could cause increased risk for infectious diseases?

 

 

Session 11:       3/29/04   Cancer and AIDS

Guest Lecturer:  Andrew Baum, Ph.D.

 

Fawzy, F.I., Fawzy, N.W., Hyuan, C.S., et al.  (1993) Malignant melanoma -- Effects of an

early structured psychiatric intervention, coping, and affective state on recurrence and survival 6

years later.  Archives of General Psychiatry, 50, 681-689.

 

Goodwin, P.J., Leszcz, M., Ennis, M., Koopmans, J., Vincent, L., Guther, H., Drysdale, E.,

 Hunderby, M., Chochinov, H.M., Navarro, M., Speca, M., & Hunter, J. (2001). The effect of

 group psychosocial   support on survival in metastatic breast cancer.  New England Journal of

 Medicine, 345, 1719-1726. 

 

Helgeson, V.S., Cohen, S., Schulz, R., Yasko, J. (2001) Long-term effects of educational

and peer discussion group interventions on adjustment to breast cancer.  Health Psychology 20,

387-392.

 

Ickovics, J.R., Hamburger, M.E., Vlahov, D., Schoenbaum, E.E., Schuman, P., Boland, R.J.,

 Moore, J., for the HIV Epidemiology Research Study Group.  (2001).  Mortality and

 CD4+  lymphocyte decline associated with chronic depressive symptoms among women with

 HIV: prospective longitudinal analyses from the HIV Epidemiological Research Study (HERS).

 Journal of the American Medical Association, 285, 1466-1474.

 

                 Assignment: Can psychosocial interventions affect the course of recovery from cancer?

                 What issues need to be considered in designing a psychosocial intervention?

 

 

Session 12: CVD   4/5/04  Cardiovascular Diseases

 

         Carroll, D., Davey Smith, G., Shipley, M.J., Steptoe, A., Brunner, E.J., & Marmot, M.G. 

            (2001). Blood pressure reactions to acute psychological stress and future blood pressure status: A

         1-year follow-up of men in the Whitehall II study.  Psychosomatic Medicine, 63, 737-743. 

 

            Kamarck, T.W., Everson, S.A., Kaplan, G.A., Manuck, S.B., Jennings, J.R., Salonen, R., &

            Salonen, J.T.   (1997).  Exaggerated blood pressure responses during mental stress are associated

            with enhanced carotid atherosclerosis in middle-aged Finnish men: Findings from the Kuopio

            Ischemic Heart Disease Study.  Circulation, 96, 3842-3848.

 

            Manuck, S.B., Marsland, A.L., Kaplan, J.R., & Williams, J.K.  (1995).  The pathogenicity of

            behavior and its neuroendocrine mediation:  An example from coronary artery disease. 

            Psychosomatic Medicine, 57, 275-283.

 

            Rozanski, A., Blumenthal, J.A., & Kaplan, J. (1999).  Impact of psychological factors on the

            pathogenesis of cardiovascular disease and implications for therapy.  Circulation, 99, 2192-2197. 

 

            Assignment:  Based on the existing evidence, is cardiovascular reactivity to stress a risk

            factor for cardiovascular disease? What studies need to be done to firmly establish it as a

            risk factor?

 

            Lecture: Type A/Hostility

 

 

Session 13:                   4/12/04            STUDENT PRESENTATIONS

 

Session 14:                   4/19/04            STUDENT PRESENTATIONS

 

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